CIPZEN D PLUS TABLET

💊🔥 Triple Action Pain Relief: Diclofenac 50mg + Paracetamol 325mg + Serratiopeptidase 10mg

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🧾 Overview

This combination medication of Diclofenac, Paracetamol (Acetaminophen), and Serratiopeptidase is used to manage acute pain, inflammation, and swelling in conditions such as:

• Musculoskeletal injuries (sprains, strains)

• Dental pain

• Post-surgical inflammation

• Arthritis and spondylitis

• ENT inflammation (e.g., sinusitis, tonsillitis)

Each component has a specific role:

• Diclofenac: Non-steroidal anti-inflammatory drug (NSAID)

• Paracetamol: Analgesic and antipyretic (fever reducer)

• Serratiopeptidase: Enzyme that reduces swelling and improves healing

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🔬 How Each Ingredient Works

• Diclofenac (50 mg)
  Reduces inflammation and pain by inhibiting prostaglandins (chemicals involved in inflammation).

• Paracetamol (325 mg)
  Provides pain relief and reduces fever by acting on the hypothalamus and prostaglandin pathways.

• Serratiopeptidase (10 mg)
  Breaks down inflammatory proteins and helps reduce swelling, bruising, and fluid retention at injury sites.

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💊 How to Use

• Dosage: Typically 1 tablet 2–3 times a day, after meals (as prescribed)

• Route: Oral

• Duration: Short-term use (5–7 days recommended unless directed by physician)

• Important: Do not exceed 4 g of Paracetamol per day (from all sources)

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😕 Common Side Effects

• Gastrointestinal discomfort: Nausea, acidity, bloating, or indigestion

• Headache

• Dizziness or light-headedness

• Mild diarrhea (due to enzyme action)

• Loss of appetite

These are usually mild and resolve with continued use or dose adjustment.

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🚨 Serious Side Effects (Seek Immediate Attention)

• Gastrointestinal bleeding or ulcers: Black stools, abdominal pain, vomiting blood

• Liver toxicity (mainly from Paracetamol overdose): Yellowing of skin/eyes, fatigue, dark urine

• Kidney dysfunction: Reduced urine output, swelling in legs

• Severe allergic reaction: Rash, itching, facial swelling, difficulty breathing

• Blood disorders (rare): Easy bruising, unusual bleeding

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🩺 Monitoring & Follow-Up

• Liver function tests (LFTs): For those using it more than a few days or with liver disease

• Kidney function tests (RFTs): Especially in elderly or dehydrated patients

• Gastrointestinal monitoring: For patients with a history of ulcers

• Regular pain assessment: To evaluate need for continued therapy

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⚠️ Warnings & Precautions

• Avoid in:

  • Active peptic ulcer or GI bleeding

  • Severe liver or kidney disease

  • Hypersensitivity to NSAIDs or Paracetamol

• Use with caution in:

  • Patients on anticoagulants (e.g., warfarin)

  • Asthmatics (may worsen symptoms)

  • Pregnant women (especially in the third trimester)

  • Chronic alcohol users (increased liver toxicity risk)

• Drug Interactions:

  • Other NSAIDs

  • Blood thinners

  • Methotrexate

  • Lithium

• Do not combine with alcohol – increases liver risk

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✅ Summary

Diclofenac + Paracetamol + Serratiopeptidase offers effective multi-targeted pain relief, addressing inflammation, pain, and swelling in acute conditions. It is especially useful for traumatic injuries, post-operative care, and inflammatory joint disorders. While effective, short-term use is advised to minimize risks like gastric ulcers or liver damage. Always take under medical supervision with appropriate monitoring.

Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.