Description
➤ ETORICOXIB 60 mg TABLET: RELIEF WITH PRECISION
Overview
Etoricoxib 60 mg is a prescription medication belonging to a class of drugs known as COX-2 selective inhibitors. It is primarily used to manage pain and inflammation associated with various chronic and acute musculoskeletal conditions. Unlike traditional NSAIDs, Etoricoxib targets the COX-2 enzyme selectively, minimizing gastrointestinal side effects while offering potent anti-inflammatory and analgesic effects.
Key Uses
Etoricoxib 60 mg is indicated for:
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Osteoarthritis (OA) – Long-term relief of joint pain and stiffness.
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Rheumatoid Arthritis (RA) – Management of inflammation and swelling.
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Ankylosing Spondylitis (AS) – Alleviates spinal pain and stiffness.
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Gouty Arthritis – Short-term treatment for acute gout flare-ups.
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Chronic Low Back Pain – As part of a comprehensive treatment plan.
Mechanism of Action
Etoricoxib works by inhibiting the COX-2 enzyme, which plays a key role in the production of prostaglandins, substances that cause inflammation, pain, and swelling. By sparing the COX-1 enzyme (which protects the stomach lining), Etoricoxib reduces pain without significantly increasing the risk of gastric ulcers or bleeding, a common concern with non-selective NSAIDs.
Dosage and Administration
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Typical dose: 60 mg once daily.
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Route: Oral, with or without food.
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Special considerations:
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In acute gout, higher doses (up to 120 mg) may be used short-term.
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Not recommended for long-term use in individuals with significant cardiovascular risk.
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Always follow your healthcare provider’s instructions regarding dosage and duration.
Benefits
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Rapid onset of action – noticeable relief often within hours.
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Once-daily dosing – enhances compliance.
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Lower risk of gastrointestinal side effects compared to traditional NSAIDs.
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No significant effect on platelet function, thus less risk of bleeding compared to aspirin.
Possible Side Effects
Though generally well-tolerated, Etoricoxib may cause:
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Mild side effects: Headache, dizziness, heartburn, nausea.
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Serious risks (rare): Elevated blood pressure, cardiovascular events (especially with prolonged use), liver enzyme abnormalities, and kidney impairment.
Precautions
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Avoid in patients with:
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Active peptic ulcers or bleeding disorders.
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Severe hepatic or renal impairment.
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Established ischemic heart disease, stroke, or peripheral arterial disease.
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Caution in elderly patients and those on diuretics or other NSAIDs.
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Not approved for use in children or adolescents under 16.
Drug Interactions
May interact with:
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Warfarin – increased risk of bleeding.
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ACE inhibitors / ARBs – may reduce kidney function.
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Diuretics – potential for fluid retention and hypertension.
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Methotrexate – may elevate blood levels of methotrexate.
Conclusion
Etoricoxib 60 mg tablet offers a targeted approach to pain management, especially for individuals with chronic inflammatory conditions. While it offers a safer gastrointestinal profile than traditional NSAIDs, it must be used cautiously due to potential cardiovascular and renal risks. Always use under medical supervision and report any unusual symptoms promptly.
Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.
