PRIMOLUT-N TABLET

💊 Norethisterone 5mg Tablet – Timely Control of Menstrual Cycles

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🔬 What is Norethisterone 5mg?

Norethisterone 5mg is a synthetic progestogen, derived from 19-nortestosterone, used to regulate menstrual disorders and hormonal imbalances in women. It mimics the action of natural progesterone, a hormone essential for menstrual cycle regulation, ovulation control, and endometrial stability.

This 5mg strength is commonly prescribed for short-term hormonal therapy, providing effective relief in menstrual irregularities.

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✅ Uses / Indications

Norethisterone 5mg is used to manage several gynecological and menstrual conditions:

• Delayed menstruation (for travel, exams, or special occasions)

• Heavy menstrual bleeding (menorrhagia)

• Irregular periods

• Painful menstruation (dysmenorrhea)

• Premenstrual syndrome (PMS)

• Endometriosis

• Secondary amenorrhea (absence of periods not due to pregnancy)

• Occasionally as part of hormonal replacement therapy (HRT) or in treatment of breast cancer (off-label, under specialist care)

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🧪 Composition / Ingredients

Each tablet contains:

• Active Ingredient: Norethisterone 5mg

• Excipients (may vary by brand):

  • Lactose monohydrate

  • Maize starch

  • Magnesium stearate

  • Povidone

  • Talc

  • Coloring agents (e.g., iron oxide)

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⚠️ Precautions and Warnings

Use Norethisterone 5mg only under medical supervision. Key precautions include:

• Pregnancy: Do not use if pregnant or planning to conceive.

• Breastfeeding: Passes into breast milk; consult a doctor before use.

• Thrombosis risk: Not recommended in patients with current or history of blood clots, stroke, or deep vein thrombosis.

• Liver conditions: Avoid if there is liver disease or jaundice.

• Hormone-sensitive cancers: Contraindicated in breast or uterine cancer unless used under oncology guidance.

• Migraine, epilepsy, asthma, or heart/kidney disorders: Use cautiously.

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💥 Side Effects

Common:

• Nausea

• Breast tenderness

• Headache

• Bloating

• Mood changes

• Spotting or breakthrough bleeding

Less Common but Serious:

• Blood clots (leg pain/swelling, chest pain, breathlessness)

• Vision problems

• Jaundice or liver function changes

• Severe headaches

• Allergic reactions (rash, swelling)

Seek immediate medical help if symptoms of a clot or allergic reaction appear.

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📋 Dosage and Administration

• Typical dose: One tablet (5mg) once to three times daily, depending on the condition.

• For period delay: Start 3 days before expected menstruation and continue as advised (usually for 10–14 days).

• For heavy or irregular bleeding: May be taken during the luteal phase of the cycle for several days.

• Take with water at the same time each day; may be taken with or without food.

Always follow your doctor’s exact instructions regarding dose and duration.

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🔄 Drug Interactions

Inform your doctor about all other medications. Key interactions include:

• Enzyme inducers (e.g., phenytoin, rifampicin): May reduce effectiveness

• Anticoagulants (e.g., warfarin): Monitor INR closely

• St. John’s Wort and some herbal supplements: May decrease hormone levels

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📌 Conclusion

Norethisterone 5mg is a versatile and effective treatment for a range of menstrual and hormonal disturbances. It offers predictable cycle control, supports endometrial health, and provides relief from PMS and irregular periods. As with any hormone therapy, it must be used under medical supervision to avoid complications, especially for women at risk of thrombosis or hormone-sensitive conditions.