PEGFIBER GRANULES 155GM

🚽🌿💊 Polyethylene Glycol 3350 + Ispaghula Husk Granules: Gentle Yet Effective Relief from Constipation

Polyethylene Glycol 3350 (PEG 3350) + Ispaghula Husk granules offer a dual-action therapy for the treatment and prevention of constipation, especially in individuals suffering from chronic constipation, irritable bowel syndrome (IBS), or post-surgical bowel irregularities. This combination blends a synthetic osmotic laxative (PEG 3350) with a natural bulk-forming fiber (Ispaghula husk or psyllium), providing a gentle, effective, and well-tolerated solution to restore normal bowel movements without straining or irritation.

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🔬 Mechanism of Action

This combination targets constipation in two synergistic ways:

🔹 Polyethylene Glycol 3350 (PEG 3350)

• An osmotic laxative that holds water in the stool by binding to it in the colon

• Softens hard stools and increases their volume

• Stimulates natural peristalsis (bowel movement) without causing cramps or urgency

• Not absorbed systemically, making it safe for long-term use

🔹 Ispaghula Husk (Psyllium)

• A natural, plant-based soluble fiber that absorbs water and swells in the intestine

• Increases stool bulk and triggers mechanical bowel stimulation

• Normalizes stool consistency in both constipation and mild diarrhea

• Helps in gut flora balance and blood sugar control (secondary benefits)

Together, they provide bulk, hydration, and motility enhancement, making this combination highly effective in managing various types of bowel irregularities.

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📌 Indications and Uses

This combination is used for:

• Chronic constipation

• Occasional constipation in elderly or sedentary individuals

• Irritable bowel syndrome (IBS) with predominant constipation (IBS-C)

• Constipation during pregnancy (under medical advice)

• Post-operative bowel regulation

• Hemorrhoid-associated constipation (softens stools to reduce straining)

• Bowel prep (in higher PEG doses)

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💊 Dosage and Administration

• Usually taken once or twice daily, as directed by a physician

• Dissolve the recommended amount of granules in a glass of water or juice

• Drink immediately, followed by another glass of water

• Do not take dry – may cause choking or blockage

• Should be taken at least 1 hour before or after other medications

Effects typically begin within 24–72 hours of regular use.

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⚠️ Precautions and Warnings

• Must be taken with adequate fluid intake to avoid intestinal blockage

• Use with caution in:

  • Patients with bowel obstruction

  • Severe dehydration

  • Known hypersensitivity to any component

• Not for immediate relief (not a stimulant laxative)

• May not be suitable in cases of sudden, unexplained bowel changes or abdominal pain—medical evaluation is necessary

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🤒 Side Effects

Common:

• Bloating or gas (especially initially)

• Mild abdominal discomfort

• Increased bowel frequency

Rare:

• Allergic reaction (rash, itching, swelling)

• Electrolyte imbalance (with long-term use without supervision)

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🔄 Drug Interactions

• May affect absorption of oral medications taken close in time (space 1–2 hours apart)

• Not known to have significant systemic drug interactions

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🧊 Storage Instructions

• Store in a cool, dry place (15–30°C)

• Keep container tightly closed and away from moisture

• Keep out of reach of children

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📝 Conclusion

Polyethylene Glycol 3350 + Ispaghula Husk granules provide a safe, effective, and well-balanced approach to constipation relief. By combining osmotic hydration with natural fiber bulk, this dual-action formula supports regular, comfortable bowel movements without harsh side effects. Ideal for both short-term and long-term use, especially when lifestyle changes alone aren’t enough.