ACECLO PLUS TABLET

💊 Aceclofenac 100mg + Paracetamol 325mg Tablet Overview

Introduction

Aceclofenac 100mg + Paracetamol 325mg is a commonly prescribed combination medication used to relieve pain and inflammation in various conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, dental pain, and musculoskeletal injuries.

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🧪 Ingredients and Their Use

• Aceclofenac (100mg): A non-steroidal anti-inflammatory drug (NSAID) that works by inhibiting the action of cyclooxygenase (COX) enzymes, thereby reducing the production of prostaglandins (chemicals responsible for pain, swelling, and inflammation).

• Paracetamol (325mg): Also known as acetaminophen, it works mainly in the brain to block pain signals and reduce fever. It enhances the pain-relieving effects of Aceclofenac and helps control fever if present.

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💡 How to Use

• Dosage: Typically taken 1 tablet twice daily after meals to minimize gastrointestinal irritation.

• Administration: Swallow the tablet whole with water. Do not crush or chew unless advised.

• Duration: Follow your doctor’s instructions. Avoid long-term use without medical supervision.

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🤕 Common Side Effects

• Nausea or vomiting

• Indigestion or abdominal pain

• Diarrhea or constipation

• Dizziness or drowsiness

• Heartburn

These side effects are usually mild and temporary. Taking the tablet with food may reduce gastric discomfort.

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⚠️ Serious Side Effects (Seek Immediate Medical Help)

• Stomach ulcers or bleeding (black or bloody stools, vomiting blood)

• Liver damage (yellowing of the skin/eyes, dark urine)

• Kidney dysfunction (reduced urine output, swelling of legs/feet)

• Allergic reactions (rash, itching, swelling, breathing difficulty)

• Elevated blood pressure or worsening heart conditions

Such effects are rare but may occur with long-term or high-dose use.

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🩺 Monitoring & Follow-Up

• Liver function tests (LFTs): Paracetamol can affect liver enzymes, especially in overdose.

• Kidney function tests (KFTs): NSAIDs like Aceclofenac can impair kidney function.

• Complete blood count (CBC): To monitor for signs of gastrointestinal bleeding.

• Blood pressure monitoring: Required for patients with cardiovascular risk.

• Regular follow-up: Especially in elderly patients or those with chronic illnesses.

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⚠️ Warnings & Precautions

• Avoid alcohol: Increases the risk of liver damage with paracetamol.

• Pregnancy & lactation: Use only if clearly needed and prescribed.

• Pre-existing conditions: Caution in patients with liver disease, kidney disease, or peptic ulcer.

• Driving or operating machinery: May cause dizziness or drowsiness.

• Drug interactions: Avoid with other NSAIDs, blood thinners (warfarin), or certain antibiotics.

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📌 Summary

Aceclofenac 100mg + Paracetamol 325mg is an effective combination for short-term relief of pain and inflammation. It offers synergistic action—Aceclofenac for inflammation and Paracetamol for pain/fever. However, it should be used under medical supervision due to risks of liver, kidney, and gastrointestinal side effects, especially with long-term use. Regular monitoring and adherence to dosing guidelines ensure both efficacy and safety.

Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.