ACIVIR 800 DT TABLET

💊 Acyclovir 800mg Tablet

(High-Strength Antiviral for Herpes Virus Infections)

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🧪 What Is Acyclovir 800mg?

Acyclovir 800mg is a high-dose antiviral medication used to treat serious or extensive viral infections caused by herpesviruses, especially:

• Herpes Zoster (Shingles)

• Severe Genital Herpes

• Chickenpox (Varicella)

• Herpes Simplex in Immunocompromised Patients

It does not cure herpes infections but helps to reduce the severity, duration, and recurrence of outbreaks, and may prevent complications when started early.

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🔬 Active Ingredient & Mechanism

• Acyclovir (800mg): A synthetic purine nucleoside analog that converts into acyclovir triphosphate inside infected cells. This active form inhibits viral DNA polymerase, thereby stopping viral replication.

Its action is selective to virus-infected cells, minimizing harm to normal human cells.

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💡 How to Use

• Standard Dosage:

  • Herpes Zoster (Shingles): 800mg five times daily for 7 to 10 days

  • Chickenpox (Varicella): 800mg four times daily for 5 days

  • Severe HSV in immunocompromised patients: As per doctor’s advice

• Administration: Take the tablet whole with water, with or without food. Ensure adequate hydration during treatment to prevent kidney damage.

• Timing: Space doses evenly (e.g., every 4 hours while awake) to maintain drug levels.

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🤕 Common Side Effects

Usually mild and temporary:

• Nausea or vomiting

• Diarrhea or abdominal discomfort

• Dizziness or headache

• Fatigue or malaise

• Skin rash (mild)

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⚠️ Serious Side Effects (Seek Immediate Medical Attention)

Rare but potentially serious:

• Kidney damage: Decreased urine output, swelling, back pain

• Neurological effects: Confusion, agitation, tremors, hallucinations, seizures — more common in elderly or those with kidney issues

• Severe allergic reaction: Hives, swelling of face/lips, difficulty breathing

• Blood disorders: Unexplained bruising or bleeding (very rare)

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🩺 Monitoring & Follow-Up

Essential in high-risk groups such as elderly or immunocompromised:

• Renal Function Tests (Creatinine, BUN): Especially important due to risk of nephrotoxicity.

• Neurological observation: Monitor for signs of confusion or agitation in older patients.

• Hydration status: Encourage plenty of fluids to prevent crystallization of the drug in the kidneys.

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⚠️ Warnings & Precautions

• Kidney Disease: Dose adjustment is essential; risk of drug accumulation.

• Pregnancy & Lactation: Generally considered safe, but use under medical supervision.

• Elderly Patients: Increased risk of side effects; monitor closely.

• Avoid Dehydration: Maintain good fluid intake throughout treatment.

• Drug Interactions: Use cautiously with nephrotoxic drugs (e.g., cyclosporine, tacrolimus).

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📌 Summary

Acyclovir 800mg is a potent antiviral tablet indicated for herpes zoster (shingles), chickenpox, and severe herpes infections. It works by inhibiting viral DNA replication, helping to shorten the duration and intensity of outbreaks and speed up healing. This higher strength is particularly useful for adults with shingles or immunocompromised individuals. While generally safe, it requires careful monitoring in patients with renal impairment, and maintaining adequate hydration is key to avoiding kidney-related side effects.

Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.