ACUCLAV DRY SYRUP

🌟 AMOXYCILLIN 200mg + CLAVULANIC ACID 28.5mg/5ml SYRUP: BALANCED POWER FOR PEDIATRIC INFECTIONS 🌟

Amoxycillin 200mg + Clavulanic Acid 28.5mg per 5ml syrup is a moderate-strength antibiotic suspension tailored for children, particularly in the age group of 3 months to 12 years, depending on weight and clinical condition. This combination medication is widely used to treat bacterial infections that are resistant to amoxicillin alone, providing a balanced yet potent treatment option in pediatric care.

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🔬 Composition and Mechanism of Action

• Amoxycillin (200mg/5ml): A broad-spectrum beta-lactam antibiotic from the penicillin class. It works by inhibiting the synthesis of bacterial cell walls, leading to the lysis and death of the bacteria.

• Clavulanic Acid (28.5mg/5ml): A beta-lactamase inhibitor. It binds to and inactivates beta-lactamase enzymes produced by some bacteria, which would otherwise degrade amoxycillin. By doing so, it extends the antibiotic’s spectrum to include resistant strains.

This synergistic combination effectively combats both non-resistant and beta-lactamase-producing bacteria.

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💊 Uses and Indications

This syrup is ideal for treating mild to moderate bacterial infections in children, such as:

• Ear infections (otitis media)

• Tonsillitis and pharyngitis

• Sinusitis

• Bronchitis and mild pneumonia

• Urinary tract infections

• Skin and soft tissue infections

• Dental infections

It is frequently prescribed when bacterial resistance is suspected, or when symptoms are not resolving with standard antibiotics.

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⚠️ Precautions and Contraindications

Precautions:

• Should be given with food to enhance absorption and reduce stomach upset.

• Shake the bottle well before each dose to ensure proper dispersion of ingredients.

• Dosing should be based on the child’s weight and severity of the infection, as directed by a physician.

• Complete the full course, even if the child feels better early.

Contraindications:

• Known allergy to penicillins, cephalosporins, or clavulanic acid.

• History of liver problems or jaundice related to amoxicillin-clavulanate.

• Use cautiously in children with renal impairment or gastrointestinal diseases.

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🚨 Side Effects

Most children tolerate the syrup well, but some may experience:

• Common: Diarrhea, nausea, vomiting, mild skin rash

• Occasional: Oral thrush (candidiasis), abdominal discomfort

• Rare/Serious: Liver enzyme changes, allergic reactions (rash, swelling, itching), severe diarrhea (possibly C. difficile), anaphylaxis

Parents should monitor for signs of allergic reactions or persistent diarrhea, and seek medical help if serious symptoms occur.

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🧊 Storage and Handling

• After reconstitution, store in the refrigerator (2°C–8°C).

• Use within 7 days, and discard any remaining syrup after this period.

• Do not freeze.

• Keep tightly closed and out of children’s reach.

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📋 Additional Notes

• Only use under pediatric supervision.

• Avoid giving unnecessary antibiotics to prevent resistance.

• Use the provided measuring device for accurate dosing.

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Amoxycillin 200mg + Clavulanic Acid 28.5mg/5ml syrup strikes a perfect balance between strength and safety. It offers reliable action against common and resistant pediatric infections, making it a go-to antibiotic option for clinicians. When used correctly, it ensures rapid recovery while minimizing the risks associated with antibiotic misuse.