🔷 DUAL-ACTION PAIN RELIEF + GASTROPROTECTION FORMULA
Aceclofenac 200mg (SR) + Rabeprazole 20mg (EC) Tablet
COMPOSITION:
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Aceclofenac 200 mg – Sustained Release (SR)
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Rabeprazole Sodium 20 mg – Enteric-Coated (EC)
PRODUCT OVERVIEW:
This fixed-dose combination tablet is formulated to deliver effective and sustained anti-inflammatory action alongside gastric mucosal protection. It pairs Aceclofenac, a potent NSAID, with Rabeprazole, a proton pump inhibitor, to offer a well-balanced solution for chronic pain conditions that require long-term NSAID use.
HOW IT WORKS:
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Aceclofenac 200 mg (SR):
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A derivative of diclofenac, it inhibits COX-2 preferentially, thereby reducing the synthesis of prostaglandins that mediate inflammation and pain.
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The sustained-release formulation ensures a steady therapeutic effect over an extended period, improving patient compliance and reducing the need for multiple daily doses.
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Rabeprazole Sodium 20 mg (EC):
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Inhibits the H⁺/K⁺ ATPase pump in the stomach lining, significantly reducing gastric acid secretion.
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Enteric coating protects the active drug from stomach acid degradation, allowing absorption in the intestine and targeted action.
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Provides effective gastroprotection, especially important during prolonged NSAID therapy.
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THERAPEUTIC INDICATIONS:
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Osteoarthritis
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Rheumatoid arthritis
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Ankylosing spondylitis
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Chronic lower back pain
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Post-traumatic or post-operative inflammation
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NSAID-induced gastric protection in at-risk populations
ADVANTAGES:
✅ Long-lasting pain relief with once-daily dosing
✅ Reduces stiffness, swelling, and joint inflammation
✅ Helps prevent NSAID-associated gastric ulcers and dyspepsia
✅ Better patient adherence due to fixed-dose convenience
✅ Suitable for patients requiring long-term pain management
DOSAGE & USAGE:
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Recommended Dose: One tablet once daily, preferably before meals to enhance absorption and maximize gastroprotection.
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Duration should be determined based on clinical response and physician’s guidance.
PRECAUTIONS:
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Caution in patients with:
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Peptic ulcer history
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Hepatic or renal dysfunction
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Cardiovascular disease
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Avoid combining with other NSAIDs or corticosteroids unless prescribed.
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Routine monitoring of renal and liver function is advised in long-term therapy.
POSSIBLE SIDE EFFECTS:
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Mild: Nausea, headache, bloating, dyspepsia
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Moderate: Constipation, dizziness, flatulence, dry mouth
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Rare but serious: Gastrointestinal bleeding, skin hypersensitivity, liver enzyme elevation, anaphylaxis
CONTRAINDICATIONS:
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Hypersensitivity to either Aceclofenac or Rabeprazole
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Active gastrointestinal bleeding or ulcer
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Severe hepatic or renal impairment
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Pregnancy and lactation (unless clearly needed and prescribed)
STORAGE CONDITIONS:
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Store below 25°C, protected from light and moisture.
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Keep out of reach of children.
NOTE:
This summary is intended for informational purposes only. Medication should be used strictly under the supervision of a registered healthcare professional.
Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.
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