Description
💊 Aceclofenac 100mg + Paracetamol 325mg + Serratiopeptidase 15mg Tablet Overview
Introduction
This triple combination tablet is widely used to treat pain, inflammation, and swelling caused by conditions such as arthritis, sports injuries, post-surgical swelling, dental pain, or musculoskeletal disorders. It combines an NSAID, an analgesic-antipyretic, and a proteolytic enzyme for a synergistic effect.
🧪 Ingredients and Their Uses
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Aceclofenac (100mg): A non-steroidal anti-inflammatory drug (NSAID) that inhibits prostaglandins, reducing inflammation and pain.
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Paracetamol (325mg): Also known as acetaminophen, it enhances the analgesic effect and helps reduce fever.
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Serratiopeptidase (15mg): A proteolytic enzyme that reduces inflammation and swelling by breaking down abnormal proteins at the inflammation site. Commonly used post-surgery or injury for faster healing.
💡 How to Use
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Dosage: Typically 1 tablet twice daily, preferably after meals.
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Route: Oral. Swallow whole with water.
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Do not chew/crush. Prolonged use should only be under medical supervision.
🤕 Common Side Effects
Most are mild and transient:
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Nausea, vomiting
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Stomach discomfort, bloating
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Heartburn, indigestion
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Dizziness, drowsiness
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Mild diarrhea
Taking it with food reduces gastrointestinal symptoms.
⚠️ Serious Side Effects
Seek immediate medical attention if the following occur:
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Stomach bleeding or ulcers (vomiting blood, black stools)
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Liver damage (yellowing of skin/eyes, dark urine, fatigue)
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Kidney issues (reduced urination, swelling of feet/ankles)
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Allergic reactions (rash, facial swelling, difficulty breathing)
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Severe skin reactions like Stevens-Johnson syndrome (rare but serious)
Long-term or unsupervised use increases these risks.
🩺 Monitoring & Follow-Up
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Liver Function Tests (LFTs): Especially important due to paracetamol.
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Renal Function Tests (KFTs): NSAIDs may impair kidney function.
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Complete Blood Count (CBC): To detect any hidden gastrointestinal bleeding.
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Blood pressure monitoring: For those with heart conditions.
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Inflammatory markers (CRP/ESR): To track treatment effectiveness.
Regular follow-up is advised, especially in chronic users or elderly patients.
⚠️ Warnings & Precautions
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Alcohol: Avoid alcohol to reduce liver toxicity risk.
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Pregnancy & Breastfeeding: Use only when prescribed. Serratiopeptidase should be avoided during pregnancy.
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Elderly patients: Increased risk of GI bleeding and kidney impairment.
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Pre-existing conditions: Caution in liver, kidney, heart diseases, or stomach ulcers.
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Drug Interactions: Avoid with other NSAIDs, anticoagulants (warfarin), methotrexate, lithium, or certain antibiotics.
📌 Summary
Aceclofenac + Paracetamol + Serratiopeptidase is a potent combination for treating pain, swelling, and inflammation from various causes. Aceclofenac and paracetamol provide pain relief, while serratiopeptidase aids in faster healing by reducing tissue swelling. Though generally well-tolerated, the tablet should be used under medical supervision due to potential liver, kidney, and gastrointestinal side effects. Routine monitoring and adherence to dosage are essential for safe use.
Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.
