AGINAL 10 TABLET

Overview:

Amlodipine 10mg Tablet is a widely prescribed medication used for the treatment of hypertension (high blood pressure) and angina pectoris (chest pain due to heart-related causes). It belongs to a group of drugs known as calcium channel blockers (CCBs). The active ingredient, Amlodipine, works by relaxing the smooth muscles of the blood vessels, thereby helping blood flow more easily. This lowers blood pressure and reduces the workload on the heart.

Mechanism of Action:

Amlodipine works by blocking calcium channels in the muscle cells of the heart and blood vessels. Calcium plays a key role in the contraction of muscles, including those that line blood vessels. By blocking the entry of calcium, Amlodipine causes the blood vessels to relax and widen (a process called vasodilation). This leads to improved blood flow, reduced blood pressure, and decreased oxygen demand by the heart, which helps in preventing episodes of angina.

Therapeutic Uses:

• Hypertension: Amlodipine is highly effective in lowering elevated blood pressure. By keeping blood pressure in check, it helps prevent serious cardiovascular events such as strokes, heart attacks, and kidney problems.

• Stable Angina: It is used to prevent and reduce chest pain caused by restricted blood flow to the heart during physical activity or emotional stress.

• Variant Angina (Prinzmetal’s Angina): Amlodipine can relieve chest pain caused by spasms in the coronary arteries, improving overall cardiac function.

Dosage and Administration:

Amlodipine 10mg is typically taken once daily, at the same time each day, with or without food. The exact dosage and duration of treatment depend on the individual’s condition, age, and response to therapy. It’s important not to miss doses and not to stop taking the medicine abruptly without consulting a healthcare provider.

Possible Side Effects:

Common side effects may include:

• Swelling in the ankles or feet (edema)

• Headache

• Dizziness or light-headedness

• Flushing

• Fatigue

• Nausea

Most side effects are mild and temporary. However, if you experience severe dizziness, irregular heartbeat, or signs of an allergic reaction such as rash, itching, or difficulty breathing, seek medical attention immediately.

Precautions:

• Liver Disease: Patients with liver impairment should use this medication cautiously.

• Pregnancy and Breastfeeding: Use only if clearly needed and prescribed by a doctor.

• Heart Conditions: Should be used with care in patients with heart failure or aortic stenosis.

• Drug Interactions: Amlodipine may interact with other medications, including beta-blockers, antifungals, and certain antibiotics. Inform your doctor about all medicines you are taking.

Storage Instructions:

Store Amlodipine 10mg tablets at room temperature (below 30°C), away from moisture, heat, and direct sunlight. Keep out of the reach of children.

Conclusion:

Amlodipine 10mg is a reliable and effective medication for managing blood pressure and preventing angina. With once-daily dosing and a strong safety profile, it plays a vital role in long-term cardiovascular health. It should always be taken under medical supervision for best results.

Would you like this tailored for a pharmacy listing or patient information leaflet?