CANDIDERMA CREAM

🧴💊🦠 Triple Action Cream: Beclometasone 0.025% + Clotrimazole 1% + Gentamicin 0.1% – Comprehensive Skin Infection Relief

The combination of Beclometasone 0.025%, Clotrimazole 1%, and Gentamicin 0.1% in a topical cream or ointment provides a potent triple-action therapy for the treatment of mixed skin infections caused by fungi, bacteria, and inflammation. This formulation is frequently prescribed for dermatological conditions involving itching, redness, swelling, and secondary infection, especially in areas like underarms, groin, or folds of the skin.

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🔬 Mechanism of Action

This medication works through the combined effects of its three active agents:

1. Beclometasone (0.025%) – A Corticosteroid

   • Reduces inflammation, redness, and itching

   • Inhibits inflammatory cells and mediators

   • Useful in controlling eczema, dermatitis, and allergic rashes

2. Clotrimazole (1%) – An Antifungal

   • Broad-spectrum activity against fungi and yeasts (e.g., Candida, Trichophyton)

   • Disrupts fungal cell membrane, causing cell death

   • Effective in ringworm, athlete’s foot, and candidiasis

3. Gentamicin (0.1%) – An Antibiotic

   • A powerful aminoglycoside that kills gram-negative and some gram-positive bacteria

   • Inhibits bacterial protein synthesis

   • Treats secondary bacterial infections in skin lesions

Together, these components offer symptomatic relief and tackle multiple causes of skin irritation.

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📌 Indications

This triple-combination cream is commonly prescribed for:

• Fungal skin infections with bacterial superinfection

• Tinea corporis/cruris/pedis (body, groin, and foot fungal infections)

• Intertrigo with secondary infection

• Infected eczema or dermatitis

• Candidiasis of the skin

• Seborrheic dermatitis

Ideal for moist, inflamed, or folded areas prone to infection and irritation.

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💡 Directions for Use

• Clean and dry the affected area before application

• Apply a thin layer 2–3 times daily or as directed

• Avoid using for more than 2 weeks continuously unless advised

• Wash hands after application unless treating hands

• Do not cover with airtight bandages unless prescribed

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⚠️ Precautions & Warnings

• For external use only

• Avoid contact with eyes, nose, mouth, or broken skin

• Not recommended for children under 12 years without medical advice

• Do not apply on acne, viral infections (e.g., herpes), or tubercular lesions

• Prolonged use may cause skin thinning, stretch marks, or resistance

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🤒 Possible Side Effects

Common:

• Mild burning or irritation at site

• Skin dryness or peeling

Serious (rare with proper use):

• Skin thinning (atrophy)

• Allergic rash or worsening of condition

• Superinfection or resistance with overuse

Stop use and consult a doctor if symptoms persist or worsen.

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🔄 Storage

• Store below 25°C in a cool, dry place

• Keep away from children

• Do not freeze or expose to direct sunlight

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📝 Conclusion

The Beclometasone + Clotrimazole + Gentamicin cream is a versatile, effective triple therapy for inflammatory fungal skin infections complicated by bacterial involvement. By targeting inflammation, fungi, and bacteria simultaneously, it ensures faster relief, healing, and control of symptoms. However, proper usage and duration are key to avoid resistance or side effects. Always use under medical supervision.

Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.