CLOBYTE GM GOLD CREAM

🧴🛡️🌿 Clobetasol 0.05% + Miconazole 2% + Neomycin 0.5% Cream: Triple-Action Formula for Inflammatory and Infected Skin Conditions

The combination of Clobetasol Propionate 0.05%, Miconazole Nitrate 2%, and Neomycin Sulphate 0.5% forms a powerful topical treatment that provides anti-inflammatory, antifungal, and antibacterial benefits in a single formulation. It is commonly prescribed for various infected skin conditions that involve redness, itching, fungal or bacterial infections, and inflammation.

This triple combination is designed for short-term use under medical supervision to quickly relieve symptoms, stop the spread of infection, and promote skin healing.

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🔬 Mechanism of Action

This formulation works through the synergistic actions of three active ingredients:

🔹 Clobetasol Propionate (0.05%) – Potent corticosteroid

• Reduces redness, swelling, and itching

• Suppresses local immune response and inflammation

• Provides quick relief in inflammatory dermatoses like eczema or psoriasis

🔹 Miconazole Nitrate (2%) – Broad-spectrum antifungal

• Disrupts fungal cell membranes by inhibiting ergosterol synthesis

• Effective against dermatophytes, Candida, and yeasts

• Treats fungal skin infections like ringworm, athlete’s foot, and candidiasis

🔹 Neomycin Sulphate (0.5%) – Topical antibiotic

• Inhibits bacterial protein synthesis

• Kills gram-negative and some gram-positive bacteria

• Helps prevent or treat secondary bacterial infections of the skin

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📌 Indications and Uses

This combination cream is used for treating:

• Fungal skin infections with inflammation (e.g., tinea corporis, tinea cruris, candidiasis)

• Infected eczema or dermatitis

• Bacterial superinfection of fungal lesions

• Intertrigo with secondary infection

• Psoriasis with secondary fungal or bacterial components

• Seborrheic dermatitis

It is ideal for mixed skin infections where fungus, bacteria, and inflammation are all present.

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💡 Dosage and Application

• Apply a thin layer to the affected area once or twice daily or as directed by a physician

• Use on intact skin only

• Do not bandage or occlude unless directed

• Do not apply near eyes, mouth, or genitals

• Duration of use: Typically limited to 7–14 days

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⚠️ Precautions and Warnings

• For external use only

• Not for long-term or widespread application

• Prolonged use can lead to:

  • Skin thinning (atrophy)

  • Resistance to antibiotics or antifungals

  • Hormonal effects (especially in children)

• Avoid in:

  • Viral skin infections (e.g., herpes, chickenpox)

  • Open wounds or deep skin lesions

  • Known hypersensitivity to any component

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🤒 Side Effects

Common:

• Mild burning or stinging at application site

• Dryness or irritation

• Itching or redness (initially)

Serious/Rare:

• Skin atrophy or stretch marks

• Perioral dermatitis

• Superinfection due to prolonged use

• Allergic contact dermatitis

Discontinue use and consult a doctor if severe irritation, allergic reaction, or worsening of symptoms occurs.

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🧊 Storage Instructions

• Store at 15–25°C, away from moisture and direct sunlight

• Keep out of reach of children

• Do not freeze

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📝 Conclusion

The Clobetasol 0.05% + Miconazole 2% + Neomycin 0.5% cream is a potent, fast-acting, triple-action topical formulation for the short-term management of infected and inflamed fungal skin conditions. It provides effective relief from itching, redness, and infection, ensuring rapid recovery when used correctly and under medical supervision.

Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.