🩺 Acotiamide 300mg Tablet: A Comprehensive Guide to Functional Dyspepsia Treatment

Acotiamide 300mg is an extended-release (ER) tablet primarily used to treat functional dyspepsia (FD), a condition characterized by chronic upper abdominal discomfort, bloating, and early satiety without an identifiable organic cause. Unlike traditional acid-suppressive therapies, acotiamide enhances gastric motility and accommodation, addressing the underlying pathophysiology of FD.

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🧪 Key Ingredients and Mechanism of Action

• Acotiamide Hydrochloride Hydrate (300mg): Acotiamide is a gastroprokinetic agent that works by:

  • Inhibiting acetylcholinesterase, leading to increased acetylcholine levels in the enteric nervous system.

  • Enhancing gastric smooth muscle contraction and improving gastric accommodation.

  • Accelerating gastric emptying time, thereby reducing postprandial fullness and bloating.

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💊 Dosage and Administration

• Dosage: One 300mg extended-release tablet per day.

• Administration: Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet.

• Timing: Take the tablet approximately 30 minutes before the main meal of the day, or as directed by your healthcare provider.

• Storage: Store in a cool, dry place away from direct sunlight and out of reach of children.

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⚠️ Common Side Effects

Most individuals tolerate acotiamide well. However, some may experience:

• Gastrointestinal discomfort (nausea, diarrhea, constipation)

• Headache

• Fatigue

• Dizziness

These side effects are generally mild and transient. If they persist or worsen, consult your healthcare provider.

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⚠️ Serious Side Effects

Serious side effects are rare but may include:

• Severe allergic reactions (e.g., rash, itching, swelling, difficulty breathing)

• Elevated liver enzymes, indicating potential liver stress

Seek immediate medical attention if you experience any of these symptoms.

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🩺 Monitoring and Follow-Up

• Liver Function: Periodic monitoring of liver enzymes is recommended, as acotiamide may cause mild elevations.

• Symptom Assessment: Regular follow-up with your healthcare provider to evaluate the effectiveness of treatment and adjust dosage if necessary.

• Drug Interactions: Inform your doctor about all medications you are taking, as acotiamide may interact with certain drugs affecting gastrointestinal motility or cholinergic activity.

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⚠️ Warnings and Precautions

• Hypersensitivity: Do not use if allergic to acotiamide or any of its components.

• Gastrointestinal Obstruction: Avoid use in patients with mechanical gastrointestinal obstruction.

• Pregnancy and Breastfeeding: Safety during pregnancy and breastfeeding has not been fully established. Use only if prescribed by a doctor.

• Liver and Kidney Disorders: Use with caution in patients with liver or kidney impairment.

• Elderly Patients: Use with caution, as older adults may be more prone to side effects.

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✅ Summary

Acotiamide 300mg extended-release tablet is an effective treatment for functional dyspepsia, targeting the underlying motility issues rather than merely suppressing stomach acid. While generally well-tolerated, it’s essential to use this medication under medical supervision, especially for individuals with existing health conditions or those on other medications. Regular monitoring and adherence to prescribed dosages will help ensure optimal therapeutic outcomes.

Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.