CTD 12.5 TABLET

💊 Chlorthalidone 12.5mg Tablet

Effective Control for Blood Pressure & Fluid Retention

Introduction:
Chlorthalidone 12.5mg tablet is a widely prescribed medication used to manage high blood pressure (hypertension) and edema (fluid retention). Classified as a thiazide-like diuretic, Chlorthalidone helps reduce the amount of water retained in the body, easing pressure on blood vessels and the heart. Its long-acting nature makes it especially effective for maintaining stable blood pressure throughout the day.

Mechanism of Action:
Chlorthalidone works by inhibiting sodium and chloride reabsorption in the kidneys, specifically in the distal convoluted tubule. This action increases the excretion of sodium, water, and certain electrolytes, leading to a decrease in blood volume and vascular resistance. The result is a consistent reduction in blood pressure and a relief in symptoms associated with fluid overload.

Therapeutic Uses:

• Hypertension: To reduce the risk of heart attack, stroke, and kidney damage.

• Edema: Associated with conditions like congestive heart failure, liver cirrhosis, or kidney disorders.

• Calcium-containing Kidney Stones: Used off-label to prevent recurrent stone formation.

Dosage & Administration:

• The usual adult dose is 12.5mg once daily, preferably taken in the morning to avoid nocturnal urination.

• It can be taken with or without food, but consistency in timing is key for optimal effect.

• Never adjust the dose without consulting a healthcare provider.

Benefits:

• Maintains stable blood pressure

• Reduces fluid overload and swelling

• Long-acting effect supports once-daily dosing

• Decreases cardiovascular risk over time

Side Effects:
Like all medications, Chlorthalidone may cause side effects. Common ones include:

• Dizziness or lightheadedness

• Increased urination

• Electrolyte imbalances (especially low potassium)

• Muscle cramps or weakness

Serious but rare side effects include:

• Irregular heartbeat

• Severe dehydration

• Allergic reactions or skin rashes

It’s important to monitor blood pressure, kidney function, and electrolyte levels regularly while taking this medication.

Precautions:

• Inform your doctor of any existing medical conditions such as diabetes, kidney or liver problems, or gout.

• Caution is advised in older adults and patients on multiple medications due to increased risk of dehydration and electrolyte imbalances.

• Avoid alcohol as it can enhance dizziness or fainting.

• Not recommended during pregnancy unless specifically advised by a doctor.

Drug Interactions:
Chlorthalidone may interact with:

• Lithium (risk of toxicity)

• Other antihypertensive drugs

• NSAIDs (may reduce effectiveness)

• Diabetic medications (may alter blood sugar levels)

Storage:

• Store at room temperature in a dry place.

• Keep the tablet in its original packaging and out of reach of children.

Conclusion:
Chlorthalidone 12.5mg is a trusted, effective, and affordable solution for managing hypertension and fluid retention. With proper use, regular follow-ups, and lifestyle changes such as a low-sodium diet and regular exercise, it can greatly improve long-term cardiovascular health and quality of life.

Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.