Product Description
Glimepiride 3mg + Metformin 1000mg is a high-strength oral anti-diabetic medication used in the management of Type 2 Diabetes Mellitus (T2DM). It is specially formulated for patients who require stronger glycemic control and have not responded adequately to diet, exercise, or lower-dose antidiabetic therapies.
This fixed-dose combination tablet targets both insulin secretion and insulin resistance, the two major abnormalities in Type 2 diabetes. It provides effective control of both fasting and postprandial (after-meal) blood glucose levels.
Active Ingredients and Their Actions
1. Glimepiride (3mg)
-
Class: Sulfonylurea
-
Mechanism: Stimulates pancreatic beta cells to increase insulin secretion.
-
Key Benefit: Helps lower blood glucose levels after meals.
2. Metformin (1000mg)
-
Class: Biguanide
-
Mechanism: Decreases liver glucose production, delays intestinal glucose absorption, and improves insulin sensitivity.
-
Key Benefit: Controls fasting blood sugar levels and supports weight neutrality or mild weight loss.
Together, these agents work synergistically to provide comprehensive and sustained blood sugar control.
How to Use
-
Dosage: Typically taken once or twice daily, as directed by your physician.
-
When to Take: Always take with meals, preferably breakfast and/or dinner, to reduce the risk of gastrointestinal side effects and hypoglycemia.
-
Method: Swallow the tablet whole with water. Do not chew or crush.
Important: Maintain a balanced diet, follow a regular exercise routine, and monitor blood glucose levels as recommended by your healthcare provider.
Common and Serious Side Effects
Common Side Effects
-
Metformin-related: Nausea, bloating, diarrhea, stomach discomfort, metallic taste in the mouth.
-
Glimepiride-related: Dizziness, headache, mild hypoglycemia (especially if a meal is missed), and potential weight gain.
These symptoms are generally mild and may reduce over time.
Serious Side Effects (Rare)
-
Severe Hypoglycemia: Symptoms include sweating, confusion, rapid heartbeat, blurred vision, or fainting.
-
Lactic Acidosis (Metformin-related): A rare but life-threatening condition. Signs include muscle pain, breathing difficulty, fatigue, and abdominal pain.
-
Allergic Reactions: Rash, itching, swelling of the face or throat, or difficulty breathing.
Seek immediate medical attention if any severe symptoms appear.
Precautions and Warnings
-
Not suitable for patients with Type 1 Diabetes or diabetic ketoacidosis.
-
Use with caution in those with kidney, liver, or heart disease.
-
Avoid excessive alcohol intake—it increases the risk of hypoglycemia and lactic acidosis.
-
Always inform your doctor about other medications or supplements to avoid interactions.
-
Regular monitoring of blood glucose and renal function is essential during long-term use.
Conclusion
Glimepiride 3mg + Metformin 1000mg offers an effective high-dose combination for patients needing stronger control over their Type 2 Diabetes. With proper diet, exercise, and regular medical supervision, this medication helps maintain stable glucose levels and reduces the risk of complications.
Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.
Reviews
There are no reviews yet.