ECOSPRIN GOLD 40 CAPSULE

Medication Overview

Aspirin 75mg + Atorvastatin 40mg + Clopidogrel 75mg is a combination therapy often prescribed for the prevention of cardiovascular events, especially in patients with a history of heart attack, stroke, or other forms of atherosclerotic disease. This combination works synergistically to reduce the risk of blood clots and lower cholesterol levels.

• Aspirin (75mg): A nonsteroidal anti-inflammatory drug (NSAID) that works as an antiplatelet agent. It prevents blood clot formation by inhibiting the enzyme COX, which reduces thromboxane A2.

• Clopidogrel (75mg): An antiplatelet medication that blocks the P2Y12 component of ADP receptors on the platelet surface, preventing platelet aggregation.

• Atorvastatin (40mg): A statin that reduces cholesterol production in the liver, thereby lowering LDL (“bad” cholesterol) and triglycerides while modestly increasing HDL (“good” cholesterol).

This combination is commonly used in secondary prevention of cardiovascular conditions, particularly in patients post-myocardial infarction, post-angioplasty, or with peripheral artery disease.

Safety Advice

1. Before Taking This Medication:

• Inform your doctor if you have bleeding disorders, liver or kidney disease, gastric ulcers, or a history of hemorrhagic stroke.

• Avoid this combination if you are allergic to aspirin, clopidogrel, or statins.

2. Drug Interactions:

• Avoid combining with NSAIDs (like ibuprofen), blood thinners (warfarin, heparin), or strong CYP3A4 inhibitors (like certain antifungals and HIV protease inhibitors).

• Excessive alcohol use can increase the risk of liver damage and stomach bleeding.

3. Pregnancy & Breastfeeding:

• Not recommended during pregnancy or breastfeeding, especially due to the risks associated with aspirin and statins. Consult your physician for safer alternatives.

Storage Instructions

• Store the medication in a cool, dry place below 25°C (77°F).

• Keep it away from direct sunlight and moisture.

• Ensure that the medication is out of reach of children and pets.

• Do not use after the expiration date printed on the packaging.

Important Notes

• Adherence to prescribed dosage is crucial. Do not adjust the dose without consulting your doctor.

• Regular monitoring of liver enzymes, lipid levels, and platelet function may be recommended.

• Watch for signs of bleeding (such as black stools, prolonged bleeding, or unusual bruising), which require immediate medical attention.

• Common side effects include gastric irritation, muscle pain, headache, and easy bruising.

• In case of missed doses, take it as soon as you remember. Do not double the dose to make up for a missed one.

• This combination is usually taken once daily, preferably after meals to reduce gastric discomfort.

Conclusion

The combination of Aspirin 75mg, Clopidogrel 75mg, and Atorvastatin 40mg is a highly effective regimen for preventing cardiovascular events in at-risk patients. When used under proper medical supervision and with attention to potential side effects and interactions, it significantly improves long-term cardiovascular health outcomes.