FLURISONE 0.1% EYE DROP

👁️💧🛡️ Fluorometholone 0.1% Eye Drops: Steroidal Relief for Ocular Inflammation

Fluorometholone 0.1% is a topical corticosteroid eye drop used to treat inflammation of the eyes due to various causes such as allergies, post-operative irritation, and inflammatory eye diseases. It helps relieve redness, swelling, itching, and discomfort by suppressing inflammatory responses in the eye tissues. Due to its low intraocular penetration, Fluorometholone is considered a safer option compared to stronger corticosteroids for short-term use in treating mild to moderate anterior segment inflammation.

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🔬 Mechanism of Action

Fluorometholone (FML) is a synthetic glucocorticoid that acts locally in the eye to inhibit multiple inflammatory mediators. It:

• Suppresses the migration of leukocytes

• Inhibits prostaglandin and cytokine production

• Reduces capillary permeability and fibroblast activity

This results in decreased tissue edema, fibrin deposition, and inflammatory cell infiltration, effectively reducing the symptoms of ocular inflammation.

Unlike other steroids like dexamethasone, FML has lower risk of increasing intraocular pressure (IOP), making it suitable for patients with mild steroid responsiveness.

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📌 Indications and Uses

Fluorometholone 0.1% eye drops are indicated for:

• Post-operative inflammation (e.g., cataract or LASIK surgery)

• Allergic conjunctivitis

• Uveitis (anterior)

• Iritis and episcleritis

• Corneal injury or trauma-induced inflammation

• Contact lens-related irritation

• Inflammatory response to chemical or thermal burns

It is typically prescribed short-term to avoid potential steroid-related complications.

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💧 Dosage and Administration

• Typical dose: 1 drop in the affected eye(s) 2 to 4 times daily

• In severe cases: 1 drop every 2 hours, then taper gradually

• Shake well before use

• Wash hands before and after application

• Do not touch dropper tip to avoid contamination

• Contact lenses should be removed before application and can be reinserted after 15 minutes

Always follow the ophthalmologist’s instructions regarding duration and tapering to prevent rebound inflammation.

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⚠️ Precautions and Warnings

• Prolonged use can cause:

  • Increased intraocular pressure (IOP)

  • Glaucoma

  • Cataract formation

• Regular eye pressure monitoring is advised with extended use

• Avoid in active eye infections, especially:

  • Herpes simplex keratitis

  • Fungal or tuberculosis-related infections

• Use cautiously in:

  • Patients with a history of glaucoma

  • Those with thin corneas or sclera

• Pregnancy and breastfeeding: Use only if clearly needed and prescribed

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🤒 Side Effects

Common:

• Temporary stinging or burning

• Blurred vision

• Eye redness

• Dryness or tearing

Rare/serious:

• Eye pain or swelling

• Vision changes

• Signs of infection (e.g., discharge, crusting)

• Prolonged elevated IOP

Report any vision changes or increased discomfort promptly.

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🔄 Drug Interactions

• Can interact with other steroid-containing or IOP-raising eye drops

• Avoid mixing with live vaccines or other drops unless advised

• If using multiple eye medications, space doses 5–10 minutes apart

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🧊 Storage Instructions

• Store at 15–25°C in a dry place

• Keep bottle tightly closed

• Discard 28 days after opening

• Keep out of reach of children

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📝 Conclusion

Fluorometholone 0.1% eye drops provide effective and well-tolerated relief from ocular inflammation with lower risk of side effects compared to stronger corticosteroids. Ideal for post-surgery recovery and allergic eye conditions, it offers a gentle yet powerful option for soothing inflammation when used under careful medical supervision.

Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult your healthcare provider for personalized recommendations.