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GLUCORYL 2 TABLET

Glimepiride 2mg

Alkem Laboratories Ltd

Description

Description

Product Description

Glimepiride 2mg is an oral antidiabetic medication from the sulfonylurea class, prescribed for the management of Type 2 Diabetes Mellitus (T2DM). It is commonly used in patients who are unable to achieve adequate glycemic control through diet, exercise, and first-line medications such as Metformin alone.

This medicine works primarily by stimulating the pancreas to release more insulin, a hormone that helps lower blood glucose levels. Glimepiride is known for being both potent and long-acting, making it a reliable option for daily blood sugar management, either alone or in combination with other anti-diabetic agents.


Mechanism of Action

Glimepiride lowers blood sugar through multiple mechanisms:

  • Stimulates pancreatic beta cells to increase insulin secretion.

  • Improves insulin sensitivity in peripheral tissues such as muscle and fat.

  • Enhances post-meal glucose utilization, helping manage blood sugar spikes after food intake.

Its action starts within 1 hour of ingestion and lasts up to 24 hours, making it suitable for once-daily dosing.


How to Use

  • Dosage: Typically, Glimepiride 2mg is taken once daily, preferably with breakfast or the first major meal of the day. Your doctor may adjust the dose based on your response and blood glucose levels.

  • Administration: Swallow the tablet whole with water. Do not crush or chew.

  • Important: Do not skip meals while on Glimepiride, as it may cause hypoglycemia (low blood sugar).

Lifestyle Tip: Combine this medication with a healthy diet, regular physical activity, and routine blood sugar monitoring for optimal results.


Common and Serious Side Effects

Common Side Effects

  • Hypoglycemia (low blood sugar): Symptoms include sweating, shakiness, dizziness, hunger, blurred vision, and confusion.

  • Weight gain: May occur due to increased insulin activity.

  • Mild stomach upset or headache in some individuals.

These side effects are usually temporary and improve with continued use or proper meal planning.

Serious Side Effects (Seek Immediate Medical Help)

  • Severe Hypoglycemia: Loss of consciousness, seizures, or fainting.

  • Allergic reactions: Rash, itching, swelling, or difficulty breathing.

  • Liver issues (rare): Jaundice (yellowing of skin/eyes), dark urine, or extreme fatigue.


Precautions and Warnings

  • Not recommended for patients with Type 1 Diabetes or diabetic ketoacidosis.

  • Use cautiously in people with kidney or liver impairment, and elderly patients.

  • Avoid alcohol—it can increase the risk of hypoglycemia.

  • Inform your doctor of all medications, including over-the-counter and herbal supplements, to avoid interactions.

  • Regular blood glucose monitoring and occasional liver/kidney function tests may be advised.


Conclusion

Glimepiride 2mg is a proven and effective medication for Type 2 Diabetes that helps improve insulin secretion and lower blood sugar. With proper use, regular follow-ups, and a supportive lifestyle, it can play a key role in preventing diabetes-related complications.


 

Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.

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