Description
Product Description
Glimepiride 3mg + Metformin 1000mg is a high-strength oral anti-diabetic medication used in the management of Type 2 Diabetes Mellitus (T2DM). It is specially formulated for patients who require stronger glycemic control and have not responded adequately to diet, exercise, or lower-dose antidiabetic therapies.
This fixed-dose combination tablet targets both insulin secretion and insulin resistance, the two major abnormalities in Type 2 diabetes. It provides effective control of both fasting and postprandial (after-meal) blood glucose levels.
Active Ingredients and Their Actions
1. Glimepiride (3mg)
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Class: Sulfonylurea
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Mechanism: Stimulates pancreatic beta cells to increase insulin secretion.
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Key Benefit: Helps lower blood glucose levels after meals.
2. Metformin (1000mg)
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Class: Biguanide
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Mechanism: Decreases liver glucose production, delays intestinal glucose absorption, and improves insulin sensitivity.
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Key Benefit: Controls fasting blood sugar levels and supports weight neutrality or mild weight loss.
Together, these agents work synergistically to provide comprehensive and sustained blood sugar control.
How to Use
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Dosage: Typically taken once or twice daily, as directed by your physician.
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When to Take: Always take with meals, preferably breakfast and/or dinner, to reduce the risk of gastrointestinal side effects and hypoglycemia.
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Method: Swallow the tablet whole with water. Do not chew or crush.
Important: Maintain a balanced diet, follow a regular exercise routine, and monitor blood glucose levels as recommended by your healthcare provider.
Common and Serious Side Effects
Common Side Effects
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Metformin-related: Nausea, bloating, diarrhea, stomach discomfort, metallic taste in the mouth.
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Glimepiride-related: Dizziness, headache, mild hypoglycemia (especially if a meal is missed), and potential weight gain.
These symptoms are generally mild and may reduce over time.
Serious Side Effects (Rare)
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Severe Hypoglycemia: Symptoms include sweating, confusion, rapid heartbeat, blurred vision, or fainting.
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Lactic Acidosis (Metformin-related): A rare but life-threatening condition. Signs include muscle pain, breathing difficulty, fatigue, and abdominal pain.
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Allergic Reactions: Rash, itching, swelling of the face or throat, or difficulty breathing.
Seek immediate medical attention if any severe symptoms appear.
Precautions and Warnings
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Not suitable for patients with Type 1 Diabetes or diabetic ketoacidosis.
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Use with caution in those with kidney, liver, or heart disease.
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Avoid excessive alcohol intake—it increases the risk of hypoglycemia and lactic acidosis.
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Always inform your doctor about other medications or supplements to avoid interactions.
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Regular monitoring of blood glucose and renal function is essential during long-term use.
Conclusion
Glimepiride 3mg + Metformin 1000mg offers an effective high-dose combination for patients needing stronger control over their Type 2 Diabetes. With proper diet, exercise, and regular medical supervision, this medication helps maintain stable glucose levels and reduces the risk of complications.
Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.
