Description
Product Description
This fixed-dose combination of Glimepiride 2mg, Metformin 500mg, and Voglibose 0.2mg is a powerful oral anti-diabetic formulation used in the management of Type 2 Diabetes Mellitus (T2DM). It is specially formulated for patients whose blood glucose levels are not adequately controlled by dual therapy or lifestyle changes alone.
This combination works by addressing multiple pathways of glucose metabolism: improving insulin sensitivity, stimulating insulin secretion, and delaying carbohydrate absorption. It provides excellent control over both fasting and postprandial blood sugar levels.
Active Ingredients and Mechanism of Action
1. Glimepiride (2mg)
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Class: Sulfonylurea
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Mechanism: Stimulates the pancreas to secrete insulin.
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Effect: Lowers blood glucose levels, especially after meals.
2. Metformin (500mg)
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Class: Biguanide
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Mechanism: Reduces hepatic glucose production and enhances insulin sensitivity.
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Effect: Controls fasting blood glucose and helps manage body weight.
3. Voglibose (0.2mg)
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Class: Alpha-glucosidase inhibitor
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Mechanism: Delays the digestion and absorption of carbohydrates in the intestines.
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Effect: Helps prevent sharp rises in post-meal blood sugar levels.
Together, this triple combination provides comprehensive blood sugar control for people with moderate to severe Type 2 Diabetes.
How to Use
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Dosage: As prescribed by your doctor—usually once or twice daily with meals.
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Administration: Take the tablet whole with a glass of water, preferably just before or with meals to enhance effectiveness and minimize gastrointestinal side effects.
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Lifestyle: Maintain a diabetic diet and regular exercise for optimal outcomes.
Tip: Do not skip meals while on this medication, as it may increase the risk of hypoglycemia.
Side Effects
Common Side Effects
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Metformin: Nausea, abdominal discomfort, diarrhea, metallic taste.
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Glimepiride: Dizziness, mild hypoglycemia, weight gain.
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Voglibose: Flatulence, bloating, abdominal discomfort.
These symptoms are generally mild and improve with continued use.
Serious Side Effects (Seek Medical Attention)
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Severe Hypoglycemia: Sweating, trembling, confusion, fainting (especially if a meal is missed).
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Lactic Acidosis (from Metformin): Rare but serious; symptoms include weakness, rapid breathing, and abdominal pain.
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Allergic reactions: Rash, itching, swelling of face/tongue, or breathing difficulty.
Precautions and Warnings
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Not recommended for: Type 1 Diabetes or diabetic ketoacidosis.
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Use with caution in: Patients with kidney, liver, or gastrointestinal disorders.
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Avoid alcohol: It can increase the risk of hypoglycemia and lactic acidosis.
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Inform your doctor about all other medications and supplements to avoid drug interactions.
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Monitoring required: Regular blood sugar tests and periodic kidney/liver function tests.
Conclusion
Glimepiride + Metformin + Voglibose offers a triple-targeted therapy to control Type 2 Diabetes by combining insulin stimulation, improved insulin sensitivity, and delayed carbohydrate absorption. This combination is especially useful for patients with high postprandial glucose levels.
Always take under medical supervision and combine with healthy lifestyle practices for the best long-term diabetes management.
Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.
