GLUVILDA DM 10/500 TABLET

Description

💊 Dapagliflozin 10mg + Metformin 500mg + Vildagliptin 100mg Tablets

Triple Power Diabetes Care – Targeting Sugar from All Sides

Overview

This fixed-dose combination of Dapagliflozin (10mg), Metformin (500mg), and Vildagliptin (100mg) is a once or twice-daily oral anti-diabetic therapy used to manage Type 2 Diabetes Mellitus in adults. It’s prescribed when monotherapy or dual therapy fails to achieve adequate glycemic control. This triple therapy works synergistically to control blood glucose through three unique mechanisms.

Pharmacological Class

• Dapagliflozin: SGLT2 Inhibitor
• Metformin: Biguanide
• Vildagliptin: DPP-4 Inhibitor

How the Combination Works

1. Dapagliflozin (10mg)
   • Blocks SGLT2 in kidneys, reducing glucose reabsorption
   • Promotes urinary glucose excretion
   • Aids in weight loss and reduces blood pressure
2. Metformin (500mg)
   • Reduces liver glucose production
   • Enhances insulin sensitivity
   • Slows intestinal glucose absorption
3. Vildagliptin (100mg)
   • Inhibits DPP-4 enzyme
   • Increases incretin hormones, boosting insulin release and reducing glucagon
   • Helps control post-meal glucose spikes

Indications

• Adults with Type 2 Diabetes Mellitus
• Inadequate glycemic control with dual therapy (e.g., Metformin + Dapagliflozin or Metformin + Vildagliptin)
• As part of an overall diabetes management plan including diet and exercise

How to Use

• Dosage: As directed by your doctor. Commonly once or twice daily, depending on the formulation.
• Administration: Take with meals to reduce stomach upset (especially due to metformin).
• Swallow the tablet whole with a glass of water.
• Do not skip doses and avoid abrupt discontinuation without consulting your doctor.

Benefits

• Comprehensive control of both fasting and postprandial glucose
• May support weight loss and blood pressure control
• Simplifies treatment by combining three agents in one tablet
• Reduces need for insulin in some patients

Possible Side Effects

• Dapagliflozin: Urinary tract infections, dehydration, increased urination
• Metformin: Nausea, abdominal discomfort, diarrhea
• Vildagliptin: Headache, dizziness, rare liver enzyme elevation

Rare but serious: Lactic acidosis (from metformin), genital infections (from dapagliflozin), pancreatitis (rare with vildagliptin)

Precautions

• Not suitable for Type 1 Diabetes or diabetic ketoacidosis
• Avoid in patients with severe kidney or liver dysfunction
• Regular monitoring of kidney function, liver enzymes, and blood glucose is recommended
• Stay well-hydrated to avoid dehydration-related side effects

Storage

• Store at room temperature (below 30°C)
• Keep away from direct sunlight and moisture
• Keep out of reach of children

When to Contact a Doctor

• Signs of low blood sugar (sweating, shakiness, confusion)
• Unusual fatigue, muscle pain, or breathing difficulty (possible lactic acidosis)
• Abdominal pain or persistent nausea
• Symptoms of urinary or genital infection

Conclusion

Dapagliflozin + Metformin + Vildagliptin is a powerful, convenient triple-therapy that helps patients with Type 2 Diabetes reach better glycemic control while supporting weight management and cardiovascular health. Use as prescribed and combine with a healthy lifestyle for optimal results.