IMDUR 60 TABLET

💖 Isosorbide Mononitrate 60mg Tablet: Once-Daily Angina Control with Long-Acting Nitrate Therapy

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💊 What is Isosorbide Mononitrate 60mg?

Isosorbide Mononitrate 60mg is a long-acting nitrate medication used to prevent angina pectoris (chest pain due to coronary artery disease). It works by relaxing and dilating blood vessels, which decreases the heart’s workload and improves oxygen delivery to the heart muscle. This strength is typically found in modified-release (MR) or extended-release (ER) forms, designed for once-daily use.

It is not used for immediate angina relief but for chronic prophylactic therapy.

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🔬 Active Ingredient

• Isosorbide Mononitrate 60mg (usually in extended-release form)

Common excipients (inactive ingredients):

• Hypromellose (for controlled release)

• Lactose monohydrate

• Magnesium stearate

• Microcrystalline cellulose

• Talc

• Povidone

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📋 How to Use

• Dosage: Typically one 60mg tablet once daily, usually in the morning.

• Administration: Oral, with or without food.

• Do not chew or crush; tablets must be swallowed whole to maintain extended-release effect.

• Consistency: Take at the same time daily for best results.

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✅ Indications

• Prevention of chronic stable angina

• May be used as part of long-term therapy in coronary artery disease

• Not for use in acute angina attacks

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🤕 Common Side Effects

• Headache (very common initially)

• Dizziness or light-headedness

• Flushing (skin redness/warmth)

• Nausea

• Fatigue or weakness

• Mild hypotension

These effects are usually transient and resolve as the body adjusts.

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⚠️ Serious Side Effects

• Severe hypotension (drop in blood pressure)

• Syncope (fainting)

• Fast or irregular heartbeat (tachycardia)

• Allergic reactions (rash, swelling, difficulty breathing)

• Nitrate tolerance (reduced drug effect over time)

Discontinue and seek medical attention for any severe or persistent symptoms.

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🩺 Monitoring & Follow-Up

• Monitor blood pressure regularly, especially after starting or adjusting dosage.

• Track angina frequency and exercise tolerance.

• Watch for signs of nitrate tolerance; schedule a “nitrate-free” interval if needed.

• Reassess treatment periodically to ensure continued effectiveness.

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⚠️ Warnings & Precautions

• Do NOT use with PDE5 inhibitors (e.g., sildenafil, tadalafil, vardenafil): dangerous drop in blood pressure.

• Avoid in patients with:

  • Severe hypotension

  • Shock or acute myocardial infarction

  • Severe anemia

• Use cautiously in elderly or those prone to falls

• Avoid alcohol: increases risk of hypotension.

• Pregnancy & breastfeeding: Use only if clearly needed and prescribed.

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🧾 Summary

Isosorbide Mononitrate 60mg is a long-acting nitrate prescribed for the once-daily prevention of angina in patients with coronary artery disease. It reduces the heart’s oxygen demand by widening blood vessels, helping prevent chest pain episodes. Though common side effects like headache and dizziness can occur, these often subside with time. Serious complications, such as hypotension or tolerance, require medical attention and careful dose monitoring. It is crucial not to use this drug with erectile dysfunction medications due to severe interaction risks. Overall, it offers reliable, full-day protection for patients managing stable angina.

Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.