Description
💡 Overview
This combination tablet is used for relief from musculoskeletal pain, muscle spasms, and inflammation. It provides a synergistic effect, offering both pain relief and muscle relaxation. It is especially useful in conditions like low back pain, sprains, cervical spondylosis, sciatica, and muscle strain.
🧪 Ingredients & Their Function
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Chlorzoxazone (250mg) – A centrally acting muscle relaxant that reduces muscle spasms and pain.
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Diclofenac Sodium (50mg) – A non-steroidal anti-inflammatory drug (NSAID) that relieves inflammation and pain.
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Paracetamol (325mg) – An analgesic and antipyretic used to reduce pain and fever.
Mechanism:
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Chlorzoxazone depresses reflexes in the spinal cord.
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Diclofenac inhibits prostaglandin synthesis (COX inhibition), reducing inflammation.
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Paracetamol elevates the pain threshold in the central nervous system.
✅ Uses
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Muscular pain and spasms
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Cervical/lumbar spondylosis
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Sprains and strains
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Sports injuries
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Postoperative musculoskeletal pain
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Osteoarthritis and rheumatoid arthritis (adjunct)
📋 How to Use
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Dosage: Usually 1 tablet 2–3 times daily after meals, as prescribed by a physician.
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Route: Oral, with water.
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Duration: Short-term use only; prolonged use increases the risk of side effects.
Do not exceed recommended dose.
⚠️ Common Side Effects
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Drowsiness or dizziness
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Nausea
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Heartburn or gastritis
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Stomach pain
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Headache
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Fatigue
These are typically mild and resolve with continued use or dose adjustment.
🚨 Serious Side Effects (Seek Medical Help)
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Allergic reactions: rash, swelling, difficulty breathing
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Liver damage: yellowing of skin or eyes, dark urine, fatigue
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Gastrointestinal bleeding: black/tarry stools, vomiting blood
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Kidney problems: decreased urination, swelling in legs
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Severe dizziness or fainting
🔍 Monitoring & Follow-Up
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Liver Function Tests (LFTs): Especially during prolonged use
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Kidney Function Tests (KFTs): If used long-term or in elderly
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GI Monitoring: Watch for signs of ulcers or GI bleeding
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Mental Alertness: Due to sedative effects of chlorzoxazone
⚠️ Warnings & Precautions
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Liver Disease: Use with caution — all three components are metabolized by the liver
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Kidney Impairment: Monitor function during long-term therapy
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Avoid Alcohol: Increases risk of liver toxicity and GI bleeding
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Pregnancy & Breastfeeding: Use only if prescribed
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Driving & Machinery: May cause drowsiness; avoid until you know how it affects you
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Drug Interactions: Avoid with other NSAIDs, anticoagulants, alcohol, or hepatotoxic drugs
📝 Summary
The Chlorzoxazone 250mg + Diclofenac 50mg + Paracetamol 325mg tablet is an effective triple-action medication for muscle-related pain and inflammation. It combines muscle relaxation with strong anti-inflammatory and pain-relieving effects. While highly effective for short-term use, it must be taken with caution to avoid liver, gastrointestinal, or renal side effects. Always use under medical supervision with appropriate follow-up if used beyond a few days.
Consult your doctor before use and never self-medicate.
Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.