Name: LEVENUE ORAL SOLUTION
Brand: Alkem Laboratories Ltd
SKU: 19276
Availability: InStock

Description

🧠🧪 Levetiracetam 100mg/mL Syrup – Pediatric & Adult Seizure Management

🧾 Overview

Levetiracetam 100mg/mL Syrup is an oral antiepileptic solution used to treat various forms of epilepsy. It is especially valuable for children, elderly, or patients with swallowing difficulties, where tablet forms are not suitable. It provides a flexible dosing option for partial-onset seizures, myoclonic seizures, and generalized tonic-clonic seizures.

🔬 How It Works

Levetiracetam is a broad-spectrum antiepileptic that:

Binds to synaptic vesicle protein 2A (SV2A) in the brain
Modulates neurotransmitter release
Stabilizes abnormal electrical activity
Reduces seizure frequency and intensity

Unlike older antiepileptics, it does not affect GABA or glutamate receptors, reducing the risk of sedation and drug interactions.

💊 Dosage & Administration

Form: Oral syrup
Concentration: 100mg/mL
Starting dose (children & adults): Typically 10–20 mg/kg/day in divided doses
Titration: Increased gradually based on weight, age, and response
Administration: Given with or without food, usually in 2 divided doses per day
Measuring device: Always use the provided dosing syringe or cup for accuracy

Example:
A 20kg child may start with 200mg (2mL) twice a day.

😕 Common Side Effects

Levetiracetam is generally well-tolerated, but some patients may experience:

Drowsiness or fatigue
Dizziness
Irritability or mood swings
Loss of appetite
Headache
Mild gastrointestinal symptoms: Nausea, vomiting, diarrhea

These are usually mild and diminish over time or with dose adjustment.

🚨 Serious Side Effects (Seek Medical Help)

Though rare, serious reactions include:

Behavioral issues: Depression, agitation, aggression, suicidal thoughts
Allergic reaction: Rash, hives, swelling of face/lips, difficulty breathing
Coordination problems: Ataxia, unsteady walking
Low blood counts: Unusual bruising, bleeding, frequent infections (very rare)

💡 Behavioral changes are more commonly seen in children and adolescents.

🩺 Monitoring & Follow-Up

Seizure log: Track frequency, duration, and type of seizures
Behavioral assessment: Monitor for mood changes, especially in pediatric patients
Kidney function tests: Levetiracetam is eliminated via the kidneys; dosage may need adjustment
Growth monitoring: In children using long-term therapy
No routine blood level monitoring required unless concerns arise

⚠️ Warnings & Precautions

Renal Impairment: Dose adjustment is essential
Psychiatric history: Use with caution in patients with depression or aggression
Pregnancy & Breastfeeding: Use only if prescribed; potential benefits must outweigh risks
Abrupt discontinuation: Avoid stopping suddenly to prevent withdrawal seizures
Driving/Operating machinery: Avoid until response to medication is known

✅ Summary

Levetiracetam 100mg/mL Syrup is a safe and effective oral antiepileptic formulation ideal for pediatric and geriatric populations. Its favorable side-effect profile, low interaction potential, and weight-based dosing flexibility make it a first-line choice for managing various seizure types.

Although side effects are typically mild, regular follow-up, behavioral monitoring, and dose adjustments based on kidney function are important for long-term safety and effectiveness.

Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.