Description
💊 Dapagliflozin 10 mg + Linagliptin 5 mg Tablet: Modern Dual Therapy for Type 2 Diabetes
🔹 What is Dapagliflozin + Linagliptin Tablet?
This fixed-dose combination is used to manage Type 2 Diabetes Mellitus (T2DM) in adults who need better blood sugar control. It combines two complementary medications:
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Dapagliflozin (10 mg): An SGLT2 inhibitor that works by promoting glucose excretion through urine, thereby lowering blood sugar and reducing body weight and blood pressure.
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Linagliptin (5 mg): A DPP-4 inhibitor that increases incretin levels, helping boost insulin release and suppress glucagon post meals.
Together, they target different pathways to achieve better glycemic control with low risk of hypoglycemia.
🧪 Ingredients
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Active ingredients:
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Dapagliflozin Propanediol Monohydrate equivalent to 10 mg of Dapagliflozin
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Linagliptin 5 mg
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Inactive ingredients (may vary by brand):
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Microcrystalline cellulose
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Magnesium stearate
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Colloidal silicon dioxide
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Hypromellose
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Titanium dioxide
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Always check the leaflet for specific excipients, especially for allergies.
💡 How to Use
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Dosage: Typically once daily, with or without food.
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Timing: Try to take it at the same time each day, usually in the morning.
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Hydration: Drink plenty of water to avoid dehydration from increased urination caused by Dapagliflozin.
Do not crush or chew. Swallow the tablet whole with water.
⚠️ Common Side Effects
From Dapagliflozin:
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Frequent urination
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Thirst or dry mouth
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Urinary tract infections
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Genital infections (especially in women)
From Linagliptin:
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Nasopharyngitis (cold symptoms)
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Headache
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Joint pain
🚨 Serious Side Effects
Seek urgent care if you notice:
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Ketoacidosis (rare but life-threatening): Nausea, vomiting, abdominal pain, confusion, and difficulty breathing
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Severe dehydration
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Pancreatitis: Severe abdominal pain, nausea
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Hypoglycemia: Especially when combined with insulin or sulfonylureas
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Allergic reactions: Swelling, rash, difficulty breathing
🩺 Monitoring & Follow-Up
Patients require regular follow-up:
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Blood glucose & HbA1c: Every 3–6 months
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Kidney function (eGFR): At baseline and periodically (important for Dapagliflozin use)
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Urinary tract health
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Liver enzymes if symptoms indicate possible damage
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Body weight and blood pressure may also be tracked for additional benefits
⚠️ Warnings & Precautions
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Not for Type 1 Diabetes or diabetic ketoacidosis
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Avoid in severe renal impairment (eGFR < 30 mL/min/1.73m²)
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Use caution in elderly (higher risk of dehydration)
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Increased risk of genital infections; maintain proper hygiene
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Pregnancy & Lactation: Not recommended unless clearly needed
📝 Summary
The Dapagliflozin 10 mg + Linagliptin 5 mg tablet is an effective once-daily oral therapy for adults with Type 2 Diabetes, offering benefits like weight loss, blood pressure reduction, and low hypoglycemia risk. While generally well-tolerated, it requires monitoring for kidney function, hydration, and rare complications like ketoacidosis or pancreatitis. Patients must maintain good hygiene, stay hydrated, and attend regular follow-ups to ensure safety and effectiveness.
Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.
