MEFKIND SPAS TABLET

🌪️ Dicyclomine 10mg + Mefenamic Acid 250mg Tablet: Fast-Acting Relief for Abdominal Cramps and Menstrual Pain

Overview

Dicyclomine 10mg + Mefenamic Acid 250mg tablet is a widely prescribed combination medication used to relieve abdominal cramps, spasms, and menstrual pain (dysmenorrhea). It brings together the benefits of an antispasmodic (Dicyclomine) and a non-steroidal anti-inflammatory drug (NSAID) (Mefenamic Acid), offering dual action against both the muscular contractions and inflammation responsible for abdominal discomfort.

This tablet is especially effective in treating colicky pain of gastrointestinal or gynecological origin, such as irritable bowel syndrome (IBS), dysmenorrhea, and spasmodic abdominal pain.

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💊 Composition and Mechanism of Action

1. Dicyclomine Hydrochloride (10mg):
   Dicyclomine is an anticholinergic and antispasmodic agent. It works by relaxing the smooth muscles of the gastrointestinal and uterine walls through inhibition of acetylcholine at muscarinic receptors. This reduces involuntary muscle contractions (spasms), helping to alleviate cramps and associated discomfort.

2. Mefenamic Acid (250mg):
   Mefenamic acid is a potent NSAID that inhibits the cyclooxygenase (COX) enzymes involved in prostaglandin synthesis. Prostaglandins are chemicals that cause inflammation, pain, and uterine contractions. By blocking them, mefenamic acid reduces pain, inflammation, and uterine cramping.

Together, these agents offer rapid and effective relief from pain, bloating, and cramps, making the combination ideal for gastrointestinal and menstrual-related spasmodic conditions.

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🧪 Therapeutic Uses

This combination is commonly prescribed for:

• Primary dysmenorrhea (menstrual cramps)

• Irritable Bowel Syndrome (IBS)

• Spasmodic abdominal pain

• Gastrointestinal colic

• Renal or biliary colic (supportive use)

• Post-operative or post-delivery uterine cramps

It is particularly beneficial in patients who experience both cramping and inflammation.

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📋 Dosage and Administration

• Typical dosage: One tablet 2–3 times daily, after meals or as directed by a physician.

• Route: Oral.

• Duration: Short-term use for symptomatic relief. Long-term use is discouraged without regular medical supervision.

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⚠️ Side Effects and Precautions

Common side effects:

• Dry mouth

• Nausea

• Drowsiness or dizziness

• Constipation or bloating

• Heartburn or gastric irritation

Serious (but rare) side effects:

• Allergic reactions (rash, swelling)

• Liver or kidney dysfunction (especially with prolonged NSAID use)

• Visual disturbances

• Confusion (more likely in elderly)

Precautions:

• Not recommended in patients with glaucoma, urinary retention, severe ulcerative colitis, or myasthenia gravis (due to dicyclomine).

• Avoid in individuals with known NSAID allergies, active ulcers, or bleeding disorders.

• Use with caution in the elderly due to potential anticholinergic side effects.

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🔄 Drug Interactions

• May interact with other anticholinergic drugs, increasing side effects.

• NSAID-related risks increase with concurrent use of corticosteroids, anticoagulants, or other NSAIDs.

• Alcohol should be avoided as it can worsen drowsiness and gastric irritation.

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📝 Final Thoughts

Dicyclomine + Mefenamic Acid tablet is a highly effective combination therapy for spasmodic and inflammatory abdominal conditions. It provides quick, targeted relief for pain and cramping—especially in cases of menstrual discomfort or irritable bowel syndrome. Though generally well-tolerated, its use should be short-term and under medical advice to avoid potential side effects, especially in sensitive populations.