MONIT SR 30 TABLET

💓 Isosorbide Mononitrate 30mg Tablet: Sustained Angina Prevention with Nitrate Therapy

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💊 What is Isosorbide Mononitrate 30mg?

Isosorbide Mononitrate 30mg is a long-acting nitrate medication used to prevent angina pectoris (chest pain) caused by coronary artery disease. It works by relaxing vascular smooth muscles, leading to dilation of blood vessels, thereby reducing myocardial oxygen demand and improving oxygen delivery to heart tissue.

This 30mg strength is often used as a modified-release (sustained-release) formulation, providing once-daily dosing convenience and prolonged action over 12–24 hours.

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🔬 Active Ingredient

• Isosorbide Mononitrate 30mg per tablet (usually in extended-release form)

Typical inactive ingredients:

• Hypromellose

• Lactose monohydrate

• Magnesium stearate

• Talc

• Povidone

• Cellulose compounds (for controlled release)

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📋 How to Use

• Dosage: Usually one 30mg tablet once daily, preferably in the morning.

• Administration: Oral, with or without food.

• Do not crush or chew—swallow whole to maintain extended-release effect.

• Should be taken at the same time daily to maintain consistent blood levels.

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✅ Indications

• Prevention of chronic stable angina

• May be part of a combination therapy in ischemic heart disease

• Not used for acute angina attacks

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🤕 Common Side Effects

• Headache (very common at treatment initiation)

• Dizziness

• Flushing or warmth

• Nausea or upset stomach

• Fatigue

• Low blood pressure symptoms (light-headedness)

These effects usually decrease with continued use.

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⚠️ Serious Side Effects

• Severe hypotension (especially when combined with other vasodilators)

• Syncope (fainting)

• Reflex tachycardia

• Allergic reaction: rash, swelling, difficulty breathing (rare)

• Nitrate tolerance with prolonged continuous use

Stop medication and seek medical attention if serious reactions occur.

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🩺 Monitoring & Follow-Up

• Blood pressure and pulse monitoring during early use or dose changes

• Track angina symptoms—frequency, duration, and severity

• Review for tolerance—some patients may require a nitrate-free interval

• Periodic medical reviews to adjust dose or assess the need for therapy continuation

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⚠️ Warnings & Precautions

• Do not use with PDE5 inhibitors (e.g., sildenafil, vardenafil): risk of life-threatening hypotension

• Use caution in:

  • Patients with severe hypotension

  • Volume depletion or dehydration

  • Severe anemia

• Avoid alcohol: can enhance hypotensive effects

• Not suitable for immediate relief of angina

• Pregnancy and breastfeeding: use only if clearly needed and prescribed

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🧾 Summary

Isosorbide Mononitrate 30mg tablet is a long-acting nitrate designed for the once-daily prevention of angina symptoms in patients with coronary artery disease. It functions by relaxing and dilating blood vessels, easing the heart’s workload. Most patients tolerate it well, though headaches and dizziness may occur during initiation. Monitoring of blood pressure and evaluation of angina control are essential. It must not be used for sudden chest pain and should never be combined with erectile dysfunction medications. When used properly, it helps improve exercise tolerance and reduce angina frequency, contributing to better cardiovascular health and daily life function.

Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.