MONTAIR AB TABLET

Overview

Acebrophylline 200mg + Montelukast 10mg is a combination medication used to manage chronic respiratory conditions such as asthma, chronic obstructive pulmonary disease (COPD), allergic rhinitis, and bronchitis. It offers both anti-inflammatory and bronchodilator effects, helping improve airflow and reduce symptoms like wheezing, coughing, and breathlessness.

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Active Ingredients & Mechanism

1. Acebrophylline (200mg)

   • Class: Bronchodilator and mucolytic agent

   • Mechanism: A derivative of theophylline, acebrophylline relaxes bronchial muscles and decreases mucus viscosity, enhancing mucus clearance and improving breathing.

2. Montelukast (10mg)

   • Class: Leukotriene receptor antagonist

   • Mechanism: Blocks leukotrienes, substances that cause inflammation, swelling, and constriction of airways, thereby preventing asthma and allergy symptoms.

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Indications (Uses)

• Bronchial asthma (mild to moderate)

• Chronic obstructive pulmonary disease (COPD)

• Allergic rhinitis

• Chronic bronchitis

• Cough associated with excessive mucus production

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How to Use

• Dosage: Usually one capsule daily, preferably in the evening or as prescribed by a physician.

• Administration: Take with or without food. Swallow whole with a glass of water.

• Do not crush or chew.

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Common Side Effects

• Headache

• Nausea or stomach upset

• Dry mouth

• Drowsiness

• Cough or sore throat

• Skin rash

These are usually mild and resolve with time. Inform your doctor if symptoms persist.

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Serious Side Effects (Seek Immediate Medical Attention)

• Chest pain or palpitations

• Breathing difficulty or worsening asthma symptoms

• Severe allergic reactions (rash, swelling, itching, difficulty breathing)

• Liver enzyme elevation (jaundice, dark urine)

• Behavioral changes (agitation, aggression, suicidal thoughts – linked to Montelukast)

• Seizures (rare, more likely with high doses of Acebrophylline)

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Monitoring & Follow-Up

• Liver function tests periodically, especially during long-term use

• Lung function tests (spirometry) to assess treatment effectiveness

• Psychological symptoms in patients using Montelukast, particularly in children or adolescents

• Heart rate and rhythm, especially if the patient has a history of arrhythmia

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Warnings & Precautions

• Pregnancy & Breastfeeding: Use only if clearly needed; consult your doctor.

• Kidney or Liver Impairment: Dose adjustment may be necessary.

• Avoid alcohol: It may worsen dizziness and increase liver stress.

• CNS Effects: May cause drowsiness; avoid driving or machinery if affected.

• Interaction with other drugs: Inform your doctor if using theophylline, phenytoin, or antiepileptics.

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Summary

Acebrophylline + Montelukast (200/10mg) is a powerful combination therapy for managing chronic respiratory conditions by offering anti-inflammatory, anti-allergic, bronchodilator, and mucolytic actions. It improves breathing and reduces allergic triggers. While generally safe, close monitoring is essential in long-term use to avoid liver stress, behavioral side effects, or rare allergic reactions. Always take this medication under the supervision of a healthcare professional and report any unusual symptoms promptly.

Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.