MSSUDIF CREAM

🧴🔬💪 Mometasone 0.1% + Fusidic Acid 2% Cream: Dual Action Against Inflammation and Infection

Mometasone 0.1% + Fusidic Acid 2% cream is a topical combination medication designed to treat inflammatory skin conditions complicated by bacterial infections. It brings together mometasone furoate, a potent corticosteroid, and fusidic acid, a powerful topical antibiotic. This combination offers both anti-inflammatory and antibacterial effects, making it ideal for managing skin conditions such as eczema, dermatitis, and infected psoriasis.

---

🔬 Mechanism of Action

• Mometasone Furoate (0.1%) is a medium- to high-potency corticosteroid that works by suppressing the release of inflammatory substances like prostaglandins and leukotrienes. It reduces redness, itching, swelling, and skin discomfort caused by inflammation.

• Fusidic Acid (2%) is a narrow-spectrum antibiotic that inhibits bacterial protein synthesis, particularly effective against gram-positive bacteria, including Staphylococcus aureus (common in skin infections). It helps treat and prevent secondary bacterial infections on inflamed skin.

Together, they provide symptomatic relief while controlling bacterial infection at the same time.

---

📌 Indications and Uses

This cream is typically prescribed for:

• Infected eczema

• Infected atopic or contact dermatitis

• Seborrheic dermatitis with bacterial involvement

• Infected psoriasis

• Other steroid-responsive dermatoses with a secondary bacterial infection

It is suitable for both adults and children (usually above 2 years of age), as directed by a physician.

---

💊 Dosage and Application

• Apply a thin layer to the affected area once or twice daily, depending on severity.

• Rub gently until fully absorbed.

• Duration: Usually not more than 2 weeks continuously unless advised by a doctor.

• Wash hands before and after application.

• Avoid contact with eyes, mouth, and mucous membranes.

⚠️ Do not apply to broken skin, open wounds, or extensive areas of the body without medical supervision.

---

⚠️ Precautions and Warnings

• Do not use for viral, fungal, or tuberculosis-related skin conditions.

• Prolonged use may lead to skin thinning, stretch marks, or hormonal effects, especially in children.

• Avoid occlusive dressings unless advised.

• Pregnancy and breastfeeding: Use only if clearly needed and under doctor supervision.

• Long-term or widespread use can cause systemic absorption of mometasone, leading to potential side effects.

---

🤒 Possible Side Effects

Common:

• Burning or stinging sensation at application site

• Itching

• Redness

Less common but serious:

• Skin thinning or discoloration

• Stretch marks

• Folliculitis

• Allergic rash or contact dermatitis

• Secondary fungal infections due to prolonged steroid use

Discontinue and consult a doctor if irritation worsens or persists.

---

🔄 Drug Interactions

• Rare with topical agents, but combining with other topical steroids or antibiotics may increase the risk of adverse effects.

• Systemic effects unlikely unless applied excessively or over large areas.

---

🧊 Storage Instructions

• Store at room temperature (15°C to 25°C).

• Keep the tube tightly closed and away from sunlight.

• Do not freeze. Keep out of reach of children.

---

📝 Conclusion

Mometasone 0.1% + Fusidic Acid 2% cream offers an effective dual therapy for skin conditions that involve inflammation and bacterial infection. With proper use under medical guidance, it provides fast relief from symptoms like itching, redness, and pain, while addressing the bacterial cause. However, it should be used cautiously and for short durations to avoid steroid-related side effects.

Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.