👁️‍🗨️ Moxifloxacin 0.5% + Dexamethasone 0.1% Eye Drops

Dual-Action Therapy: Infection Control with Inflammation Relief

🔍 Overview

Moxifloxacin 0.5% + Dexamethasone 0.1% Eye Drops is a combination ophthalmic solution used to treat bacterial eye infections with associated inflammation. It combines a powerful broad-spectrum antibiotic (Moxifloxacin) with a corticosteroid (Dexamethasone), offering rapid infection control while reducing pain, redness, and swelling.

💧 Active Ingredients & Mechanism

• Moxifloxacin Hydrochloride 0.5% w/v
  A fourth-generation fluoroquinolone antibiotic that works by inhibiting bacterial DNA gyrase and topoisomerase IV enzymes, leading to bacterial cell death.

• Dexamethasone 0.1% w/v
  A potent corticosteroid that reduces inflammation by inhibiting multiple inflammatory mediators, providing relief from swelling, redness, and discomfort.

📌 How to Use

• Usual Dosage:
  1 drop in the affected eye(s) 4 times daily for 5 to 7 days or as prescribed.

• Instructions:

  1. Wash hands before application.

  2. Tilt head back and gently pull down the lower eyelid.

  3. Instill one drop into the conjunctival sac.

  4. Do not touch the dropper to any surface, including the eye.

  5. Keep eyes closed for 1–2 minutes after application.

  6. Shake well before use (if suspension).

• Storage: Store at room temperature (below 25°C), avoid contamination. Discard after 28 days of opening.

✅ Common Indications

• Bacterial conjunctivitis with inflammation

• Postoperative inflammation and infection prophylaxis (e.g., after cataract surgery)

• Anterior uveitis (under physician guidance)

• Other inflammatory ocular conditions with suspected or confirmed bacterial component

⚠️ Common Side Effects

• Eye irritation or burning sensation

• Temporary blurred vision

• Dryness or watery eyes

• Redness

• Foreign body sensation

These side effects are generally mild and resolve on their own.

🚨 Serious Side Effects (Rare but Important)

• Increased intraocular pressure (IOP) – risk of glaucoma, especially with long-term use

• Cataract formation – with prolonged corticosteroid use

• Delayed wound healing

• Superinfections – fungal or viral infections may develop with long-term use

• Allergic reactions – swelling, itching, rash, eye pain, or vision changes

Seek immediate medical help if any serious symptoms occur.

🩺 Monitoring & Follow-Up

• Before Use: Rule out viral/fungal causes of eye infection

• During Treatment:

  • Monitor intraocular pressure, especially if used >10 days

  • Evaluate response to treatment after 3–5 days

• Follow-Up:

  • Eye examination if symptoms worsen or persist

  • Reassess if used for more than 2 weeks

⚠️ Warnings & Precautions

• Not for viral or fungal eye infections

• Avoid prolonged use due to steroid side effects (glaucoma, cataract)

• Do not use with contact lenses during treatment

• Use with caution in children, especially under 2 years

• Pregnancy and lactation: Use only if prescribed and necessary

• Avoid abrupt discontinuation – may cause rebound inflammation

📝 Summary

Moxifloxacin 0.5% + Dexamethasone 0.1% eye drops offer a powerful dual-approach to treating bacterial eye infections with inflammation. While highly effective, this medication should be used only under medical supervision due to potential steroid-related complications. Proper hygiene, correct dosing, and timely follow-up are key to safe and successful treatment.

Always follow your doctor’s advice, dosage instructions, and never self-medicate.