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SOMPRAZ HP COMBIPACK KIT

Original price was: ₹230.00.Current price is: ₹195.50.

SOMPRAZ HP KIT

Amoxycillin 750mg + Esomeprazole 40mg + Clarithromycin 500mg

Sun Pharmaceutical Industries Ltd

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🩺 Triple Therapy Kit for H. pylori Eradication

(Amoxycillin 750mg + Esomeprazole 40mg + Clarithromycin 500mg)


🔍 What is this Medication Kit?

This combination therapy is commonly used to treat Helicobacter pylori (H. pylori) infection, a major cause of peptic ulcers. It includes:

  1. Amoxycillin (750mg) – a broad-spectrum penicillin antibiotic that kills H. pylori.

  2. Clarithromycin (500mg) – a macrolide antibiotic that inhibits bacterial protein synthesis.

  3. Esomeprazole (40mg) – a proton pump inhibitor (PPI) that reduces stomach acid, enhancing antibiotic effectiveness and healing ulcers.


💊 How to Use the Kit

Typically taken as a 7 to 14-day regimen, often called triple therapy. Dosage may vary by brand or doctor’s instructions but generally:

  • Amoxycillin 750mg – twice daily

  • Clarithromycin 500mg – twice daily

  • Esomeprazole 40mg – once or twice daily

Take with food or as advised by a healthcare provider. Complete the full course even if symptoms improve.


⚠️ Common Side Effects

Most side effects are mild and manageable:

  • Nausea

  • Diarrhea

  • Headache

  • Metallic taste (common with clarithromycin)

  • Abdominal pain or bloating

  • Rash or mild skin reactions


🚨 Serious Side Effects (Seek Immediate Medical Attention)

Rare but potentially serious:

  • Severe allergic reaction: Swelling, rash, breathing difficulties

  • Liver toxicity: Yellowing of skin/eyes, dark urine

  • Clostridioides difficile infection: Severe diarrhea or bloody stools

  • QT prolongation: Irregular heartbeat (clarithromycin-related)

  • Severe skin reactions: Stevens-Johnson syndrome (very rare)


🔍 Monitoring & Follow-Up

Regular follow-up is important to ensure the infection is eradicated and side effects are managed.

  • Symptom review: Persistent pain, vomiting, or bleeding may indicate treatment failure.

  • Stool antigen test or urea breath test: Done 4–6 weeks post-treatment to confirm H. pylori eradication.

  • Liver/kidney function tests: If long-term therapy is needed or in patients with pre-existing conditions.


⚠️ Warnings & Precautions

  • Allergies: Avoid if allergic to penicillins, cephalosporins, or macrolides.

  • Liver/kidney impairment: Use with caution.

  • Pregnancy & breastfeeding: Clarithromycin is generally not recommended in pregnancy unless absolutely necessary.

  • Drug interactions: Clarithromycin and esomeprazole can interact with drugs like warfarin, statins, and anticonvulsants.


Summary

The Amoxycillin + Esomeprazole + Clarithromycin kit is an effective first-line treatment for H. pylori infection and associated ulcers. Taken as a short-term regimen, it combines two potent antibiotics with a PPI to kill the bacteria, reduce stomach acid, and allow ulcers to heal. While generally well tolerated, it requires careful monitoring for side effects, especially in high-risk individuals. Adherence to treatment and follow-up testing are essential for successful eradication and prevention of recurrence.

Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.

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