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NEZEN DP TABLET

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NEZEN DP TABLET

Diclofenac 50mg + Paracetamol 325mg + Serratiopeptidase 10mg

Seagull Pharmaceutical Pvt Ltd

Description

Description

💊🔥 Triple Action Pain Relief: Diclofenac 50mg + Paracetamol 325mg + Serratiopeptidase 10mg


🧾 Overview

This combination medication of Diclofenac, Paracetamol (Acetaminophen), and Serratiopeptidase is used to manage acute pain, inflammation, and swelling in conditions such as:

  • Musculoskeletal injuries (sprains, strains)

  • Dental pain

  • Post-surgical inflammation

  • Arthritis and spondylitis

  • ENT inflammation (e.g., sinusitis, tonsillitis)

Each component has a specific role:

  • Diclofenac: Non-steroidal anti-inflammatory drug (NSAID)

  • Paracetamol: Analgesic and antipyretic (fever reducer)

  • Serratiopeptidase: Enzyme that reduces swelling and improves healing


🔬 How Each Ingredient Works

  • Diclofenac (50 mg)
    Reduces inflammation and pain by inhibiting prostaglandins (chemicals involved in inflammation).

  • Paracetamol (325 mg)
    Provides pain relief and reduces fever by acting on the hypothalamus and prostaglandin pathways.

  • Serratiopeptidase (10 mg)
    Breaks down inflammatory proteins and helps reduce swelling, bruising, and fluid retention at injury sites.


💊 How to Use

  • Dosage: Typically 1 tablet 2–3 times a day, after meals (as prescribed)

  • Route: Oral

  • Duration: Short-term use (5–7 days recommended unless directed by physician)

  • Important: Do not exceed 4 g of Paracetamol per day (from all sources)


😕 Common Side Effects

  • Gastrointestinal discomfort: Nausea, acidity, bloating, or indigestion

  • Headache

  • Dizziness or light-headedness

  • Mild diarrhea (due to enzyme action)

  • Loss of appetite

These are usually mild and resolve with continued use or dose adjustment.


🚨 Serious Side Effects (Seek Immediate Attention)

  • Gastrointestinal bleeding or ulcers: Black stools, abdominal pain, vomiting blood

  • Liver toxicity (mainly from Paracetamol overdose): Yellowing of skin/eyes, fatigue, dark urine

  • Kidney dysfunction: Reduced urine output, swelling in legs

  • Severe allergic reaction: Rash, itching, facial swelling, difficulty breathing

  • Blood disorders (rare): Easy bruising, unusual bleeding


🩺 Monitoring & Follow-Up

  • Liver function tests (LFTs): For those using it more than a few days or with liver disease

  • Kidney function tests (RFTs): Especially in elderly or dehydrated patients

  • Gastrointestinal monitoring: For patients with a history of ulcers

  • Regular pain assessment: To evaluate need for continued therapy


⚠️ Warnings & Precautions

  • Avoid in:

    • Active peptic ulcer or GI bleeding

    • Severe liver or kidney disease

    • Hypersensitivity to NSAIDs or Paracetamol

  • Use with caution in:

    • Patients on anticoagulants (e.g., warfarin)

    • Asthmatics (may worsen symptoms)

    • Pregnant women (especially in the third trimester)

    • Chronic alcohol users (increased liver toxicity risk)

  • Drug Interactions:

    • Other NSAIDs

    • Blood thinners

    • Methotrexate

    • Lithium

  • Do not combine with alcohol – increases liver risk


Summary

Diclofenac + Paracetamol + Serratiopeptidase offers effective multi-targeted pain relief, addressing inflammation, pain, and swelling in acute conditions. It is especially useful for traumatic injuries, post-operative care, and inflammatory joint disorders. While effective, short-term use is advised to minimize risks like gastric ulcers or liver damage. Always take under medical supervision with appropriate monitoring.

Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.

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