NUCOXIA MR 8 TABLET

Description

💊 ETORICOXIB 60MG + THIOCOLCHICOSIDE 8MG TABLET

Advanced Relief for Inflammatory Muscle Pain

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🧾 What is Etoricoxib + Thiocolchicoside 8mg Tablet?

This combination tablet includes:

• Etoricoxib 60mg – a selective COX-2 inhibitor for anti-inflammatory and analgesic action, and

• Thiocolchicoside 8mg – a centrally acting muscle relaxant used to relieve painful muscle spasms.

The formulation is specially designed to treat acute inflammatory musculoskeletal conditions where both inflammation and muscle spasm are present. It offers rapid symptom control, better mobility, and faster recovery.

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⚙️ Mechanism of Action: How It Works

Etoricoxib (60mg):

• Inhibits cyclooxygenase-2 (COX-2) enzyme involved in pain and inflammation.

• Reduces prostaglandin production, lowering pain, redness, and swelling.

• Causes fewer gastrointestinal side effects compared to non-selective NSAIDs.

Thiocolchicoside (8mg):

• Binds to GABA-A and glycine receptors in the central nervous system.

• Promotes muscle relaxation by inhibiting spinal reflexes.

• Helps reduce painful spasms, improves mobility, and enhances comfort during recovery.

Dual Benefit:

• Simultaneous reduction in inflammation and muscle tension

• Accelerates functional recovery in back pain, joint conditions, and injuries

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📌 Indications & Uses

This combination is effective for:

• Acute low back pain and lumbago

• Cervical spondylosis

• Muscle spasms due to trauma or inflammation

• Sciatica and nerve root compression

• Orthopedic and post-surgical pain

• Painful muscular contractures

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🧪 Dosage & Administration

• Usual adult dose: 1 tablet once or twice daily, depending on symptom severity and medical advice

• To be taken after food to reduce gastric irritation

• Not recommended for children or adolescents under 16 years

• Treatment duration should be short-term (usually 5–7 days)

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⚠️ Precautions & Warnings

• Thiocolchicoside 8mg may cause sedation, drowsiness, or dizziness; avoid driving or operating machinery

• Long-term use is discouraged due to potential genotoxic effects of high-dose Thiocolchicoside

• Use caution in patients with cardiovascular disorders, hepatic or renal impairment

• Regular monitoring may be needed in elderly or multi-medicated patients

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❌ Contraindications

Do not use this combination if you:

• Have a history of allergy to NSAIDs or muscle relaxants

• Are pregnant (especially in 1st and 3rd trimesters) or breastfeeding

• Have epilepsy, convulsive disorders, or CNS-related illnesses

• Suffer from active peptic ulcer, GI bleeding, or severe liver/kidney disease

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🔍 Side Effects

Common:

• Nausea, mild gastritis

• Drowsiness, fatigue

• Headache

• Increased blood pressure

Rare/Serious:

• GI bleeding or ulcer

• Allergic skin reactions

• Seizure (in predisposed individuals)

• Liver enzyme elevation

Seek immediate medical help for chest pain, rash, or neurological symptoms.

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📦 Storage & Packaging

• Store below 30°C in a dry, cool place

• Keep away from light and moisture

• Usually available in blister strips of 10 tablets

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✅ Conclusion

The Etoricoxib 60mg + Thiocolchicoside 8mg tablet provides dual-action relief from inflammatory pain and muscle spasms, ideal for acute conditions needing rapid recovery. It combines the anti-inflammatory power of Etoricoxib with the muscle-relaxing efficiency of Thiocolchicoside, making it a reliable solution under proper medical guidance.

 Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.