Description
💊 ETORICOXIB 60MG + PARACETAMOL 325MG TABLET
Dual Action. Powerful Relief.
🧾 What is Etoricoxib + Paracetamol Tablet?
This combination tablet contains Etoricoxib 60mg, a selective COX-2 inhibitor, and Paracetamol (Acetaminophen) 325mg, a widely used analgesic and antipyretic. Together, they offer synergistic pain relief, targeting inflammation and general pain through complementary mechanisms.
It is typically prescribed for moderate to severe pain, especially where inflammation is a key contributor—such as in arthritis, musculoskeletal injuries, or dental pain.
⚙️ Mechanism of Action: How It Works
Etoricoxib (60mg):
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Selectively inhibits the cyclooxygenase-2 (COX-2) enzyme.
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Reduces production of pro-inflammatory prostaglandins.
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Minimizes gastrointestinal side effects by sparing COX-1.
Paracetamol (325mg):
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Acts centrally by blocking prostaglandin synthesis in the brain.
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Reduces pain perception and fever without significant anti-inflammatory effect.
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Has minimal gastrointestinal or cardiovascular side effects.
Combined Effect:
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Enhanced analgesia and quicker symptom relief.
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Reduced need for high doses of either drug.
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Balanced safety and efficacy.
📌 Uses & Indications
Prescribed for the short-term and long-term management of:
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Osteoarthritis
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Rheumatoid arthritis
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Low back pain
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Ankylosing spondylitis
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Post-traumatic musculoskeletal pain
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Dental or postoperative pain
🧪 Dosage & Administration
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Standard adult dose: 1 tablet once or twice daily (based on medical advice)
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To be taken with or without food, but preferably after meals to minimize gastric discomfort
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Not suitable for children under 16 years
Always use the lowest effective dose for the shortest duration necessary.
⚠️ Precautions & Warnings
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Cardiovascular risk: Etoricoxib may increase the risk of heart attack or stroke, especially with prolonged use.
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Liver function: Paracetamol can cause liver toxicity at high doses or in alcohol users.
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Kidney function: Use cautiously in patients with renal impairment.
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Avoid alcohol and other NSAIDs or acetaminophen-containing drugs concurrently.
❌ Do Not Use If You Have:
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Active stomach ulcers or gastrointestinal bleeding
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Severe hepatic or renal disease
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Known allergy to NSAIDs or paracetamol
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Uncontrolled hypertension or established cardiovascular disease
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Pregnancy (especially 3rd trimester) or breastfeeding, unless advised by a doctor
🔍 Possible Side Effects
Common:
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Nausea, indigestion
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Dizziness, headache
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Mild elevation in blood pressure
Serious (Seek Immediate Help):
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Chest pain or shortness of breath
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Liver dysfunction (yellowing of skin/eyes)
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Skin rashes, allergic reactions
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Signs of GI bleeding (black or bloody stools)
📦 Storage & Packaging
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Store in a cool, dry place below 30°C
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Protect from light and moisture
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Typically packaged in blister strips of 10 tablets
✅ Conclusion
The Etoricoxib 60mg + Paracetamol 325mg tablet delivers fast-acting, dual-mechanism pain relief, ideal for conditions with both inflammatory and non-inflammatory pain components. While generally well tolerated, it should be used under medical supervision, especially in patients with cardiovascular, liver, or kidney conditions.
Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.
