OFLOSTAR 200 TABLET

🦠👁️💊 Ofloxacin 200mg Tablet: Broad-Spectrum Antibiotic for Bacterial Infections

Ofloxacin 200mg is a broad-spectrum antibiotic belonging to the fluoroquinolone class, used to treat a wide range of bacterial infections. It is effective against both Gram-positive and Gram-negative bacteria, and works by targeting the DNA replication process of bacteria, making it highly effective in treating respiratory, urinary tract, gastrointestinal, skin, and eye infections.

Due to its rapid absorption and high tissue penetration, Ofloxacin is a commonly prescribed oral antibiotic, often used in both outpatient and hospital settings.

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🔬 Mechanism of Action

Ofloxacin inhibits two critical bacterial enzymes:

• DNA gyrase

• Topoisomerase IV

These enzymes are essential for DNA replication, transcription, repair, and recombination. By blocking them, Ofloxacin prevents bacterial multiplication and survival, leading to the elimination of the infection.

This bactericidal action makes it particularly useful in infections where rapid bacterial clearance is important.

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📌 Indications and Uses

Ofloxacin 200mg is used to treat:

• Urinary tract infections (UTIs)

• Prostatitis (prostate infections)

• Respiratory infections: bronchitis, pneumonia, sinusitis

• Skin and soft tissue infections

• Gastrointestinal infections: traveler’s diarrhea, typhoid fever

• Gynecological infections: pelvic inflammatory disease

• Eye infections (in topical form)

• Ear infections (in otic form)

Ofloxacin may also be used off-label in tuberculosis or multi-drug resistant infections, as directed by specialists.

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💊 Dosage and Administration

• Standard adult dose: 200mg twice daily, or as prescribed based on infection type and severity

• Taken with or without food, with a full glass of water

• Duration usually ranges from 5 to 10 days, depending on the infection

• Should not be taken with dairy products or calcium/iron supplements, as they may reduce absorption

• Complete the full course even if symptoms improve early

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⚠️ Precautions and Warnings

• Not recommended in:

  • Children under 18 years

  • Pregnant or breastfeeding women

• Use with caution in:

  • Elderly patients

  • Patients with kidney problems, epilepsy, or CNS disorders

• Avoid sunlight or tanning beds during use (photosensitivity risk)

• Discontinue immediately if you experience tendon pain or swelling

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🤒 Side Effects

Common side effects:

• Nausea

• Diarrhea

• Headache

• Dizziness

• Insomnia

Rare but serious:

• Tendon rupture (especially Achilles tendon)

• Seizures or convulsions

• Peripheral neuropathy (tingling or numbness)

• QT interval prolongation (heart rhythm disturbance)

• Hypersensitivity reactions (rash, breathing difficulty)

Report serious side effects to your doctor immediately.

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🔄 Drug Interactions

• Avoid combining with:

  • Antacids, zinc, iron, or calcium (space at least 2 hours apart)

  • NSAIDs (may increase risk of seizures)

  • Blood thinners (e.g., warfarin)—monitor INR levels

  • Antiarrhythmics (QT prolongation risk)

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🧊 Storage Instructions

• Store at 15–30°C

• Keep in a cool, dry place, away from sunlight and moisture

• Keep out of reach of children

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📝 Conclusion

Ofloxacin 200mg tablet is a potent and fast-acting antibiotic that targets a wide array of bacterial infections. With excellent oral bioavailability, strong tissue penetration, and broad-spectrum activity, it offers effective relief from common bacterial illnesses. When used responsibly under medical supervision, it ensures quick symptom relief and supports bacterial eradication with minimal side effects.

Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.