SILDOO M 50 TABLET

💊💧 Mirabegron 50 mg + Silodosin 8 mg Tablet

“Dual Relief for Overactive Bladder and Enlarged Prostate”
Bladder Muscle Control | Improved Urinary Flow | Daily Confidence

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📋 What is Mirabegron + Silodosin Tablet?

The Mirabegron 50 mg + Silodosin 8 mg tablet is a combination therapy used to treat urinary symptoms associated with:

• Overactive Bladder (OAB): Urgency, frequency, and urge incontinence

• Benign Prostatic Hyperplasia (BPH): Hesitancy, weak stream, and incomplete emptying

This fixed-dose combination offers dual-action relief by improving bladder muscle relaxation and reducing prostatic urethral resistance, thus enhancing both storage and voiding functions.

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🔬 Active Ingredients & Their Functions

1. Mirabegron 50 mg

   • Class: Beta-3 adrenergic agonist

   • Action: Relaxes the detrusor muscle in the bladder, increasing capacity and reducing urgency/frequency

   • Used in: OAB treatment

2. Silodosin 8 mg

   • Class: Selective alpha-1A adrenergic receptor blocker

   • Action: Relaxes smooth muscle in the prostate and bladder neck, improving urine flow

   • Used in: BPH symptom management

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💡 How to Use

• Dosage: One tablet once daily

• Timing: Preferably at the same time each day

• Administration: Take with food (important for Silodosin absorption) and swallow whole with water

• Do not crush or chew

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✅ Common Side Effects

Mirabegron-Related:

• Increased blood pressure (hypertension)

• Headache

• Constipation

• Dry mouth

• Urinary tract infection

Silodosin-Related:

• Dizziness (especially when standing up)

• Retrograde ejaculation (common but not harmful)

• Nasal congestion

• Diarrhea

• Low blood pressure (orthostatic hypotension)

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🚨 Serious Side Effects (Rare but Notable)

• Angioedema (facial, lip, tongue, or throat swelling)

• Urinary retention

• Severe allergic reactions

• Syncope (fainting) due to blood pressure drop

• Intraoperative Floppy Iris Syndrome (important for those undergoing cataract surgery)

Seek immediate medical attention for signs of allergic reaction, severe dizziness, chest pain, or breathing difficulty.

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🔍 Monitoring & Follow-Up

• Blood Pressure: Regularly monitor, especially early in treatment

• Heart Rate: Mirabegron may cause tachycardia

• Renal & Hepatic Function: Adjust dosage in impaired patients

• Symptom Tracking: Evaluate improvements in urine flow and bladder control

• Eye Surgery Disclosure: Inform ophthalmologist if using Silodosin

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⚠️ Warnings & Precautions

• Not recommended in severe hepatic or renal impairment

• Avoid concurrent use with strong CYP3A4 inhibitors (e.g., ketoconazole)

• Avoid alcohol: Increases risk of orthostatic hypotension

• Pregnancy Category: Not for use in women (primarily indicated for male urinary disorders)

• May interact with other antihypertensives, beta-blockers, or anticholinergics

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📝 Summary

Mirabegron 50 mg + Silodosin 8 mg tablet delivers comprehensive relief for men suffering from BPH and overactive bladder symptoms. Mirabegron improves bladder capacity and reduces urgency, while Silodosin enhances urinary flow by relaxing the prostate and bladder neck. This once-daily combination simplifies treatment while improving quality of life, but requires close blood pressure and symptom monitoring, especially in elderly patients or those on multiple medications.

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🌟🚻 “Stronger Control. Smoother Flow.”

Bladder and Prostate Care—Powered by Precision.

Always follow your doctor’s advice, dosage instructions, and never self-medicate.