SILOFAST M 25 TABLET

💊🔗 Mirabegron 25 mg + Silodosin 8 mg Tablet

“Dual Action Relief for Overactive Bladder and Benign Prostatic Hyperplasia”
Enhanced Bladder Control | Targeted Prostate Support

📋 What is Mirabegron + Silodosin Tablet?

Mirabegron 25 mg + Silodosin 8 mg Tablet is a combination medication designed to manage symptoms of overactive bladder (OAB) and benign prostatic hyperplasia (BPH). It combines:

• Mirabegron (25 mg): A beta-3 adrenergic agonist that relaxes the bladder muscle, increasing its capacity and reducing symptoms of urgency and frequency.

• Silodosin (8 mg): A selective alpha-1A adrenergic antagonist that relaxes the smooth muscle in the prostate and bladder neck, improving urine flow and reducing symptoms of BPH.

This combination offers a comprehensive approach to managing urinary symptoms associated with both OAB and BPH.

💡 How to Use

• Dosage:

  • Typically, one tablet daily, taken with or without food.

  • Silodosin should be taken with meals to enhance absorption.

• Administration:

  • Swallow the tablet whole; do not chew or crush.

• Duration:

  • Use as directed by a healthcare provider; do not discontinue without consulting a doctor.

🔬 Common Side Effects

• Mirabegron:

  • Elevated blood pressure

  • Dry mouth

  • Nasopharyngitis

  • Urinary tract infection

  • Headache

  • Constipation

  • Dizziness

  • Joint pain

  • Cystitis

  • Back pain

  • Upper respiratory tract infection

  • Sinusitis

  • Diarrhea

  • High heart rate

  • Fatigue

  • Abdominal pain

  • Neoplasms (cancers)

• Silodosin:

  • Dizziness

  • Orthostatic hypotension

  • Diarrhea

  • Nasal congestion

  • Tachycardia

  • Dry mouth

  • Nausea

  • Skin reactions

  • Erectile dysfunction

🚨 Serious Side Effects

• Mirabegron:

  • Angioedema (swelling of the face, lips, tongue, or throat)

  • Increased blood pressure

  • Urinary retention

  • Severe allergic reactions

• Silodosin:

  • Severe hypotension

  • Allergic reactions

  • Intraoperative floppy iris syndrome (during cataract surgery)

🔍 Monitoring & Follow-Up

• Blood Pressure:

  • Regular monitoring is essential, as Mirabegron may elevate blood pressure, while Silodosin can cause a drop, especially during the initial dose.

• Kidney Function:

  • Assess renal function periodically, as both medications are metabolized by the liver and excreted by the kidneys.

• Symptom Tracking:

  • Monitor urinary symptoms to evaluate the effectiveness of the therapy.

⚠️ Warnings & Precautions

• Contraindications:

  • Severe liver or kidney impairment

  • Known hypersensitivity to either medication

• Cautions:

  • Use with caution in patients with significant cardiovascular conditions.

  • Avoid concurrent use with strong CYP3A4 inhibitors (e.g., ketoconazole) or inducers.

• Drug Interactions:

  • Mirabegron may interact with medications metabolized by CYP2D6.

  • Silodosin may interact with strong CYP3A4 inhibitors, increasing its plasma concentration.

📝 Summary

Mirabegron 25 mg + Silodosin 8 mg Tablet is a combination therapy aimed at providing comprehensive relief from urinary symptoms associated with overactive bladder and benign prostatic hyperplasia. By targeting different pathways, it offers enhanced bladder control and improved urine flow. Regular monitoring and adherence to prescribed dosages are crucial for optimal outcomes.

🌟🛡️ “Dual Action Relief for a Balanced Bladder”

Empowering Your Urinary Health with Precision Therapy

Always follow your doctor’s advice, dosage instructions, and never self-medicate.