💖📰 MEDICATION BRIEF: ISOSORBIDE DINITRATE 10 MG TABLET
Generic Name: Isosorbide Dinitrate
Strength: 10 mg
Drug Class: Organic Nitrates / Antianginal Agent
Route: Oral Tablet
Common Brand Names: Isordil, IsoDinit, Dilatrate (varies by region and manufacturer)
💡 WHAT IT’S USED FOR
Isosorbide Dinitrate 10 mg is primarily used to prevent and manage angina pectoris—chest pain caused by coronary artery disease. By relaxing and widening the blood vessels, it increases oxygen delivery to the heart muscle, relieving chest tightness and reducing the heart’s workload. It may also be used in heart failure management, post-heart attack care, and in some cases of pulmonary hypertension, as part of combination therapy.
🔔 Note: It is used for prevention, not for relieving acute angina attacks.
🧪 INGREDIENTS
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Active Ingredient:
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Isosorbide Dinitrate 10 mg
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Common Inactive Ingredients:
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Lactose monohydrate
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Microcrystalline cellulose
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Magnesium stearate
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Talc
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Starch
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Dye or film coating agents (color varies by brand)
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⚠️ Always check for allergens and consult the pharmacist if you have dietary restrictions or sensitivities.
⚕️ HOW IT WORKS
Isosorbide dinitrate is converted to nitric oxide in the body, a molecule that causes smooth muscles in blood vessels to relax. This vasodilation reduces the heart’s oxygen demand and improves blood flow to the heart muscle, thereby preventing angina symptoms.
🚨 SIDE EFFECTS
Common Side Effects:
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Headache (very frequent and often expected)
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Dizziness
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Flushing
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Nausea
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Low blood pressure (especially when standing)
Serious (Seek medical help):
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Fainting
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Blurred vision
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Rapid heartbeat
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Severe hypotension
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Allergic reactions (rare)
💊 Tolerance Warning: Long-term use without proper dosing intervals can cause nitrate tolerance, reducing its effectiveness. Most regimens include nitrate-free periods (typically overnight).
⚠️ PRECAUTIONS AND INTERACTIONS
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Avoid with PDE-5 Inhibitors (e.g., sildenafil/Viagra): Can cause life-threatening hypotension.
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Do not consume alcohol: It can intensify dizziness and blood pressure drop.
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Use with caution in:
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Severe anemia
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Hypotension
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Glaucoma
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Recent head injury or brain hemorrhage
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Pregnancy & Breastfeeding: Only under medical advice.
🕒 DOSAGE & ADMINISTRATION
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Typically taken 2 to 3 times daily, spaced at least 6 hours apart.
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Take consistently, with or without food.
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Do not crush or chew. Swallow whole with water.
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Follow nitrate-free intervals to avoid tolerance.
Missed a dose? Take it as soon as you remember—unless it’s close to your next dose. Never double up.
📦 STORAGE INSTRUCTIONS
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Store at 20–25°C (68–77°F)
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Keep away from moisture and direct light.
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Ensure container is tightly closed and out of children’s reach.
🏁 FINAL TAKEAWAY
Isosorbide Dinitrate 10 mg is a reliable and effective medication for long-term angina prevention. Used correctly, it helps improve heart efficiency and quality of life for people with coronary heart disease. Regular monitoring, proper spacing between doses, and communication with your healthcare provider are essential for safe use.
Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.
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