SPYE TABLET

💊 SPIRAMYCIN 3 MILLION IU TABLET 💊

Precision Antibiotic Therapy | Targeted Action with Fewer Side Effects

🦠 Product Overview

Spiramycin 3 Million IU Tablet is a macrolide-class antibiotic used to treat a range of bacterial and protozoal infections, particularly those involving the respiratory tract, oral cavity, and toxoplasmosis infections. It is derived from Streptomyces ambofaciens and functions primarily as a bacteriostatic agent, although it can exert bactericidal effects at high concentrations.

This high-dose formulation (3 million IU) ensures enhanced antimicrobial potency while maintaining a favorable safety profile, making it especially useful in toxoplasmosis in pregnancy and patients sensitive to other antibiotics.

🔬 Key Features

• ✅ High-Potency Macrolide Antibiotic (3 Million IU per tablet)

• ✅ Bacteriostatic/Bactericidal Action depending on dose

• ✅ Safe Use in Pregnancy (especially for toxoplasmosis)

• ✅ Minimal Drug Resistance Development

• ✅ Oral Administration with Good GI Tolerance

⚙️ Mechanism of Action

Spiramycin works by inhibiting bacterial protein synthesis. It binds to the 50S subunit of bacterial ribosomes, blocking translocation and thus preventing the elongation of protein chains. This halts bacterial growth and replication.

It is particularly effective against:

• Toxoplasma gondii

• Streptococcus pneumoniae

• Mycoplasma, Chlamydia, and other Gram-positive organisms

📦 Packaging & Dosage

• Form: Oral tablet

• Strength: 3,000,000 IU (International Units)

• Typical Packaging: Blister packs of 10 tablets

• Standard Dosage:

  • Toxoplasmosis in pregnancy: 1 tablet every 8 hours for 3–4 weeks (cycling therapy with pyrimethamine/sulfadiazine)

  • Respiratory or dental infections: 1 tablet twice or thrice daily

  • Dosage may vary by infection severity and patient condition

Always follow physician-prescribed regimen.

⚕️ Indications

• Toxoplasmosis in pregnant women (to prevent fetal transmission)

• Respiratory tract infections (e.g., bronchitis, pharyngitis)

• Odontogenic infections (e.g., periodontitis, dental abscesses)

• Skin and soft tissue infections

• Prophylaxis in post-surgical oral infections

⚠️ Side Effects & Precautions

• Common Side Effects:

  • Nausea, abdominal discomfort, mild diarrhea

  • Metallic taste, skin rashes

• Rare but Serious:

  • Liver enzyme elevation

  • Allergic reactions (rash, swelling, difficulty breathing)

• Precautions:

  • Use with caution in patients with hepatic impairment

  • Not first-line for severe systemic infections

  • Avoid concurrent use with other macrolides or CYP3A4 inhibitors

Safe for use in pregnancy; classified as Category B.

🧴 Storage Instructions

• Store below 25°C

• Protect from moisture and direct sunlight

• Keep out of reach of children

• Use before the expiry date printed on the packaging

📝 Conclusion

Spiramycin 3 Million IU Tablet offers a potent, well-tolerated option for treating specific bacterial and protozoal infections. Particularly valuable in pregnancy-related toxoplasmosis and dental infections, it provides targeted antimicrobial action with minimal systemic burden. When used under medical guidance, it is a safe and effective tool in the clinician’s antimicrobial arsenal.

Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.