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TAXIM O CV 200 TABLET

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TAXIM O CV 200 TABLET

Cefixime 200mg + Clavulanic Acid 125mg

Alkem Laboratories Ltd

Description

Description

🧪 Cefixime 200 mg + Clavulanic Acid 125 mg Tablet: Comprehensive Overview

Cefixime 200 mg + Clavulanic Acid 125 mg tablet is a combination antibiotic used to treat a variety of bacterial infections. Cefixime is a third-generation cephalosporin antibiotic, while Clavulanic Acid is a β-lactamase inhibitor that enhances the effectiveness of Cefixime by preventing bacterial resistance.


🧬 Composition & Mechanism of Action

  • Cefixime (200 mg): Inhibits bacterial cell wall synthesis, leading to bacterial cell death.

  • Clavulanic Acid (125 mg): Inhibits β-lactamase enzymes produced by bacteria, which can destroy Cefixime, thereby enhancing its efficacy.

This combination allows for the treatment of infections caused by β-lactamase-producing bacteria that would otherwise be resistant to Cefixime alone.


💊 Indications

This combination tablet is prescribed for:

  • Uncomplicated urinary tract infections

  • Upper respiratory tract infections

  • Tonsillitis/Pharyngitis

  • Acute exacerbations of chronic bronchitis

  • Gonococcal infections

  • Otitis media

It is not effective against viral infections.


⚠️ Common Side Effects

Most side effects are mild and may include:

  • Diarrhea

  • Abdominal pain

  • Nausea

  • Dizziness

  • Indigestion

These side effects often resolve with continued use or after discontinuation of the medication.


🚨 Serious Side Effects

Although rare, serious side effects may include:

  • Severe allergic reactions (rash, itching, swelling of the face/lips/tongue)

  • Persistent or severe diarrhea, possibly with blood (signs of Clostridium difficile-associated diarrhea)

  • Jaundice (yellowing of the skin or eyes)

  • Unusual bleeding or bruising

  • Seizures

Immediate medical attention is required if any of these occur.


🩺 Monitoring & Follow-Up

Regular monitoring may be necessary, especially for individuals with:

  • Renal or hepatic impairment

  • A history of gastrointestinal disorders

  • Concurrent use of other medications

Periodic blood tests may be recommended to assess kidney and liver function and to monitor for any adverse effects.


⚠️ Warnings & Precautions

  • Allergy: Avoid if allergic to cephalosporins, penicillins, or β-lactamase inhibitors.

  • Tendon Issues: Use with caution in elderly patients or those on corticosteroids due to the risk of tendonitis or tendon rupture.

  • Seizure Disorders: Contraindicated in individuals with a history of seizures or central nervous system disorders.

  • Diabetes: May cause hypoglycemia; monitor blood sugar levels closely.

  • Pregnancy & Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding.

  • Drug Interactions: Avoid combining with antacids, multivitamins, or dairy products, as they may reduce absorption. Use caution with anticoagulants like warfarin due to increased bleeding risk.


✅ Summary

Cefixime 200 mg + Clavulanic Acid 125 mg tablet is a potent combination antibiotic effective against a wide range of bacterial infections. While generally well-tolerated, it’s essential to use this medication under medical supervision, especially for individuals with pre-existing conditions or those taking other medications. Adhering to prescribed dosages and completing the full course of treatment are crucial to ensure effectiveness and reduce the risk of antibiotic resistance.

Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.

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