TELMIKIND LNB TABLET

💊 Triple Power for Heart Health

Cilnidipine 10mg + Metoprolol Succinate 25mg + Telmisartan 40mg Tablet
Advanced Combination Therapy for Effective Blood Pressure Management

Overview:
This fixed-dose combination of Cilnidipine, Metoprolol Succinate, and Telmisartan offers a comprehensive approach to managing essential hypertension (high blood pressure) and related cardiovascular risks. Each component targets a different mechanism of blood pressure regulation, resulting in enhanced efficacy and better control with a single tablet.

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Composition and Roles:

• Cilnidipine 10mg: A calcium channel blocker (CCB), specifically a dual L/N-type blocker. It relaxes blood vessels and reduces peripheral resistance by inhibiting calcium entry into vascular smooth muscle. Additionally, it reduces sympathetic nerve activity via N-type calcium channel inhibition, offering protection to the heart and kidneys.

• Metoprolol Succinate 25mg: A cardioselective beta-1 blocker that lowers heart rate, cardiac output, and blood pressure. It is particularly effective in patients with a fast heartbeat or concurrent heart conditions such as angina or heart failure.

• Telmisartan 40mg: An angiotensin II receptor blocker (ARB) that prevents blood vessels from narrowing, thereby lowering blood pressure and improving blood flow. Telmisartan also provides renal protection, especially in diabetic patients.

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Therapeutic Uses:

• Essential hypertension (stage 1 and 2)

• Patients with comorbid conditions like diabetes, heart disease, or chronic kidney disease

• Hypertension not controlled by monotherapy

• Long-term cardiovascular risk reduction

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Dosage and Administration:

• Recommended dosage: One tablet once daily, usually in the morning.

• Administration: Can be taken with or without food.

• Compliance: The once-daily regimen improves adherence compared to taking multiple separate medications.

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Benefits:

• Multi-mechanism action for improved blood pressure control

• Renal and cardiac protection

• Reduced side effects by using moderate doses of each drug

• Improved patient compliance with single-pill convenience

• Fewer blood pressure fluctuations throughout the day

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Side Effects:

Common:

• Dizziness or lightheadedness

• Fatigue

• Slow heart rate (due to Metoprolol)

• Swelling in ankles (due to Cilnidipine)

Rare but serious:

• Electrolyte imbalance

• Hypotension (very low blood pressure)

• Bradycardia (abnormally slow heart rate)

• Allergic reactions

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Precautions:

• Not suitable for patients with severe liver or kidney impairment without physician supervision

• Monitor heart rate and blood pressure regularly

• Caution in patients with asthma, diabetes, or bradycardia

• Avoid abrupt discontinuation, especially of Metoprolol, as it may cause rebound hypertension

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Drug Interactions:

• Avoid combining with other antihypertensives without medical advice

• Can interact with NSAIDs, antidiabetic drugs, and certain antidepressants

• Alcohol may enhance blood pressure-lowering effects

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Storage:

• Store in a cool, dry place at room temperature

• Keep away from light and moisture

• Out of reach of children

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Conclusion:

This triple combination tablet is a powerful, modern solution for patients with moderate to severe hypertension or those who need enhanced blood pressure control. By combining three well-established drug classes in one pill, it simplifies therapy, improves adherence, and significantly reduces cardiovascular risks.

Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.