Description
💊 Triple Power for Heart Health
Cilnidipine 10mg + Metoprolol Succinate 25mg + Telmisartan 40mg Tablet
Advanced Combination Therapy for Effective Blood Pressure Management
Overview:
This fixed-dose combination of Cilnidipine, Metoprolol Succinate, and Telmisartan offers a comprehensive approach to managing essential hypertension (high blood pressure) and related cardiovascular risks. Each component targets a different mechanism of blood pressure regulation, resulting in enhanced efficacy and better control with a single tablet.
Composition and Roles:
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Cilnidipine 10mg: A calcium channel blocker (CCB), specifically a dual L/N-type blocker. It relaxes blood vessels and reduces peripheral resistance by inhibiting calcium entry into vascular smooth muscle. Additionally, it reduces sympathetic nerve activity via N-type calcium channel inhibition, offering protection to the heart and kidneys.
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Metoprolol Succinate 25mg: A cardioselective beta-1 blocker that lowers heart rate, cardiac output, and blood pressure. It is particularly effective in patients with a fast heartbeat or concurrent heart conditions such as angina or heart failure.
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Telmisartan 40mg: An angiotensin II receptor blocker (ARB) that prevents blood vessels from narrowing, thereby lowering blood pressure and improving blood flow. Telmisartan also provides renal protection, especially in diabetic patients.
Therapeutic Uses:
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Essential hypertension (stage 1 and 2)
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Patients with comorbid conditions like diabetes, heart disease, or chronic kidney disease
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Hypertension not controlled by monotherapy
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Long-term cardiovascular risk reduction
Dosage and Administration:
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Recommended dosage: One tablet once daily, usually in the morning.
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Administration: Can be taken with or without food.
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Compliance: The once-daily regimen improves adherence compared to taking multiple separate medications.
Benefits:
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Multi-mechanism action for improved blood pressure control
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Renal and cardiac protection
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Reduced side effects by using moderate doses of each drug
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Improved patient compliance with single-pill convenience
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Fewer blood pressure fluctuations throughout the day
Side Effects:
Common:
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Dizziness or lightheadedness
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Fatigue
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Slow heart rate (due to Metoprolol)
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Swelling in ankles (due to Cilnidipine)
Rare but serious:
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Electrolyte imbalance
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Hypotension (very low blood pressure)
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Bradycardia (abnormally slow heart rate)
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Allergic reactions
Precautions:
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Not suitable for patients with severe liver or kidney impairment without physician supervision
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Monitor heart rate and blood pressure regularly
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Caution in patients with asthma, diabetes, or bradycardia
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Avoid abrupt discontinuation, especially of Metoprolol, as it may cause rebound hypertension
Drug Interactions:
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Avoid combining with other antihypertensives without medical advice
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Can interact with NSAIDs, antidiabetic drugs, and certain antidepressants
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Alcohol may enhance blood pressure-lowering effects
Storage:
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Store in a cool, dry place at room temperature
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Keep away from light and moisture
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Out of reach of children
Conclusion:
This triple combination tablet is a powerful, modern solution for patients with moderate to severe hypertension or those who need enhanced blood pressure control. By combining three well-established drug classes in one pill, it simplifies therapy, improves adherence, and significantly reduces cardiovascular risks.
Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.
