VOMILAST OD TABLET

🤰🌿💊 Doxylamine 20mg + Vitamin B6 20mg + Folic Acid 5mg Tablet: Safe & Effective Relief for Morning Sickness in Pregnancy

The combination of Doxylamine 20mg, Vitamin B6 (Pyridoxine) 20mg, and Folic Acid 5mg is widely used to treat nausea and vomiting during pregnancy (NVP), commonly known as morning sickness. This formulation not only provides symptom relief but also supports fetal development by supplying essential vitamins. Recommended by gynecologists for its safety and efficacy, this triple-action tablet offers a non-teratogenic, FDA-approved option for expecting mothers experiencing moderate to severe nausea.

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🔬 Mechanism of Action

Each component in this combination plays a distinct and complementary role:

✅ Doxylamine (20mg) – Antihistamine

• Belongs to the H1 receptor antagonist class

• Reduces nausea, vomiting, and gastrointestinal discomfort by blocking histamine activity in the brain’s vomiting center

• Causes mild sedation, which can also ease restlessness often associated with early pregnancy nausea

✅ Vitamin B6 (Pyridoxine, 20mg) – Anti-nausea vitamin

• Plays a key role in neurotransmitter regulation

• Shown to reduce pregnancy-related nausea independently and even more when combined with Doxylamine

• Helps regulate hormonal changes that may trigger nausea

✅ Folic Acid (5mg) – Fetal neural development support

• Essential for DNA synthesis and cell division

• Helps prevent neural tube defects (NTDs) in the developing fetus

• Supports maternal red blood cell production, reducing the risk of anemia

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📌 Indications and Uses

This combination is specifically indicated for:

• Morning sickness during the first trimester of pregnancy

• Hyperemesis gravidarum (severe vomiting, often requiring hospitalization)

• Supplemental folate intake during pregnancy

This formulation may also be prescribed for nausea unrelated to pregnancy in select cases, though pregnancy-related nausea is its primary indication.

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💊 Dosage and Administration

• Usual adult dose: One tablet at bedtime

• If symptoms persist, dose may be increased to one tablet in the morning and one at bedtime, as per doctor’s advice

• Should be taken with water, not chewed or crushed

• Can be used safely during all trimesters under medical supervision

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⚠️ Precautions and Warnings

• May cause drowsiness; avoid driving or operating machinery

• Should not be taken with alcohol, other sedatives, or MAO inhibitors

• Use cautiously in women with:

  • Liver disease

  • Asthma

  • Glaucoma

  • Urinary retention

Always inform the doctor of all current medications to avoid interactions.

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🤒 Side Effects

Common:

• Drowsiness or dizziness

• Dry mouth

• Constipation

• Mild headache

Rare but serious:

• Allergic reactions (rash, swelling, itching)

• Mood changes or confusion (very rare)

Report any persistent or unusual symptoms to your healthcare provider.

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🔄 Drug Interactions

• Avoid concurrent use with CNS depressants (e.g., benzodiazepines)

• Anticholinergic drugs may enhance Doxylamine’s effects

• No significant interaction with prenatal vitamins

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🧊 Storage Instructions

• Store at 15–30°C, away from heat and moisture

• Keep out of reach of children

• Do not use after the expiry date

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📝 Conclusion

Doxylamine 20mg + Vitamin B6 20mg + Folic Acid 5mg tablet is a trusted, first-line therapy for pregnancy-related nausea and vomiting, offering relief without compromising fetal health. Its dual benefit of symptom control and prenatal nutritional support makes it a safe and effective choice for a more comfortable and healthier pregnancy journey.

Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.