💡 Overview

This combination tablet is used for relief from musculoskeletal pain, muscle spasms, and inflammation. It provides a synergistic effect, offering both pain relief and muscle relaxation. It is especially useful in conditions like low back pain, sprains, cervical spondylosis, sciatica, and muscle strain.

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🧪 Ingredients & Their Function

1. Chlorzoxazone (250mg) – A centrally acting muscle relaxant that reduces muscle spasms and pain.

2. Diclofenac Sodium (50mg) – A non-steroidal anti-inflammatory drug (NSAID) that relieves inflammation and pain.

3. Paracetamol (325mg) – An analgesic and antipyretic used to reduce pain and fever.

Mechanism:

• Chlorzoxazone depresses reflexes in the spinal cord.

• Diclofenac inhibits prostaglandin synthesis (COX inhibition), reducing inflammation.

• Paracetamol elevates the pain threshold in the central nervous system.

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✅ Uses

• Muscular pain and spasms

• Cervical/lumbar spondylosis

• Sprains and strains

• Sports injuries

• Postoperative musculoskeletal pain

• Osteoarthritis and rheumatoid arthritis (adjunct)

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📋 How to Use

• Dosage: Usually 1 tablet 2–3 times daily after meals, as prescribed by a physician.

• Route: Oral, with water.

• Duration: Short-term use only; prolonged use increases the risk of side effects.

Do not exceed recommended dose.

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⚠️ Common Side Effects

• Drowsiness or dizziness

• Nausea

• Heartburn or gastritis

• Stomach pain

• Headache

• Fatigue

These are typically mild and resolve with continued use or dose adjustment.

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🚨 Serious Side Effects (Seek Medical Help)

• Allergic reactions: rash, swelling, difficulty breathing

• Liver damage: yellowing of skin or eyes, dark urine, fatigue

• Gastrointestinal bleeding: black/tarry stools, vomiting blood

• Kidney problems: decreased urination, swelling in legs

• Severe dizziness or fainting

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🔍 Monitoring & Follow-Up

• Liver Function Tests (LFTs): Especially during prolonged use

• Kidney Function Tests (KFTs): If used long-term or in elderly

• GI Monitoring: Watch for signs of ulcers or GI bleeding

• Mental Alertness: Due to sedative effects of chlorzoxazone

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⚠️ Warnings & Precautions

• Liver Disease: Use with caution — all three components are metabolized by the liver

• Kidney Impairment: Monitor function during long-term therapy

• Avoid Alcohol: Increases risk of liver toxicity and GI bleeding

• Pregnancy & Breastfeeding: Use only if prescribed

• Driving & Machinery: May cause drowsiness; avoid until you know how it affects you

• Drug Interactions: Avoid with other NSAIDs, anticoagulants, alcohol, or hepatotoxic drugs

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📝 Summary

The Chlorzoxazone 250mg + Diclofenac 50mg + Paracetamol 325mg tablet is an effective triple-action medication for muscle-related pain and inflammation. It combines muscle relaxation with strong anti-inflammatory and pain-relieving effects. While highly effective for short-term use, it must be taken with caution to avoid liver, gastrointestinal, or renal side effects. Always use under medical supervision with appropriate follow-up if used beyond a few days.

Consult your doctor before use and never self-medicate.

Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.