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ZYBEND PLUS ORAL SUSPENSION

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ZYBEND PLUS ORAL SUSPENSION

Ivermectin 1.5mg + Albendazole 200mg

Zydus Healthcare Limited

Description

Description

🧬 IVERMECTIN + ALBENDAZOLE SUSPENSION

Dual-Action Antiparasitic Suspension: Broad Coverage in a Child-Friendly Form


COMPOSITION (per 5 mL):

  • Ivermectin 1.5 mg

  • Albendazole 200 mg


PRODUCT OVERVIEW:

This fixed-dose oral suspension combines two powerful antiparasitic agents: Ivermectin, a macrocyclic lactone, and Albendazole, a benzimidazole derivative. Together, they offer broad-spectrum deworming coverage in a single, convenient liquid formulation, ideal for children and individuals with swallowing difficulties. This combination is designed to target a wide range of intestinal and tissue parasites effectively and safely.


MECHANISM OF ACTION:

  • Ivermectin works by binding to glutamate-gated chloride channels in the nerve and muscle cells of parasites, increasing chloride ion permeability. This causes paralysis and death of the parasite.

  • Albendazole acts by inhibiting tubulin polymerization, disrupting the microtubules essential for glucose uptake. This results in energy depletion, immobilization, and parasite death.

The combination ensures both intestinal clearance and systemic efficacy, especially in mixed parasitic infections.


INDICATIONS:

This suspension is used for the treatment of various parasitic infections, including:

  • Ascariasis (roundworm)

  • Enterobiasis (pinworm)

  • Trichuriasis (whipworm)

  • Hookworm infections (Ancylostomiasis, Necatoriasis)

  • Strongyloidiasis

  • Cutaneous larva migrans

  • Filariasis (lymphatic and cutaneous forms)

  • Scabies (off-label, in conjunction with topical agents)

  • Mixed helminth infections


DOSAGE & ADMINISTRATION:

  • Children aged 2–12 years: 5 mL (1.5 mg Ivermectin + 200 mg Albendazole) as a single dose

  • Dosage may vary based on body weight and specific infection—consult a healthcare provider

  • In endemic areas, deworming may be repeated every 6 months or annually

Shake well before use
Can be taken with or without food, although a fatty meal improves Albendazole absorption


KEY BENEFITS:

Dual-action formula targeting a wider range of parasites
Convenient liquid form suitable for children
Single-dose treatment in many cases
✅ Safe and effective in mass deworming programs
✅ Helps reduce parasite-related nutritional deficiencies and growth delays


PRECAUTIONS:

  • Avoid use in pregnant women, especially in the first trimester

  • Use caution in patients with hepatic impairment

  • Monitor liver function and complete blood count (CBC) during prolonged or repeated use

  • Not recommended in children under 2 years without medical advice


POSSIBLE SIDE EFFECTS:

  • Common: Mild abdominal pain, nausea, dizziness, headache

  • Occasional: Diarrhea, fatigue, rash

  • Rare (systemic reactions): Allergic response, transient liver enzyme elevation, itching due to parasite die-off


CONTRAINDICATIONS:

  • Known hypersensitivity to ivermectin, albendazole, or related compounds

  • Severe liver disease

  • Pregnancy and lactation (unless medically advised)


STORAGE INSTRUCTIONS:

  • Store at room temperature (below 25°C)

  • Keep tightly closed and protect from light and moisture

  • Keep out of reach of children


DISCLAIMER:

This summary is for informational purposes only. Always consult a qualified healthcare professional before use. Proper diagnosis and dosing are essential for safe and effective treatment.

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