ALMOX CV 625 TABLET

💊 Amoxycillin 500mg + Clavulanic Acid 125mg Tablet

(Broad-Spectrum Antibiotic with Beta-Lactamase Inhibitor)

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🧪 What Is It?

This combination tablet contains two active ingredients used to treat a wide range of bacterial infections:

• Respiratory tract infections (e.g. sinusitis, bronchitis, pneumonia)

• Urinary tract infections (UTIs)

• Skin and soft tissue infections

• Dental infections

• Bone and joint infections

It is not effective against viral infections like the common cold or flu.

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🔬 Ingredients & Mechanism of Action

• Amoxycillin (500 mg): A broad-spectrum penicillin antibiotic that kills bacteria by inhibiting bacterial cell wall synthesis.

• Clavulanic Acid (125 mg): A beta-lactamase inhibitor that prevents resistant bacteria from inactivating amoxycillin. It enhances the effectiveness of amoxycillin against resistant strains.

Together, they form a synergistic combination to combat a wider range of bacterial infections.

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💡 How to Use

• Usual Dosage: 1 tablet every 8 or 12 hours, as directed by the physician.

• Route: Oral.

• Administration: Take with or just after food to reduce stomach upset. Swallow whole with water.

• Course Duration: Complete the full course, even if symptoms improve early.

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🤕 Common Side Effects

These are typically mild and temporary:

• Diarrhea or loose stools

• Nausea, vomiting

• Abdominal discomfort

• Skin rash or itching

• Headache

Taking the tablet with meals may help reduce gastrointestinal symptoms.

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⚠️ Serious Side Effects (Seek Immediate Medical Attention)

Rare but potentially dangerous reactions include:

• Severe allergic reactions: Hives, swelling of the face/lips/tongue, breathing difficulty

• Clostridium difficile-associated diarrhea (CDAD): Persistent watery or bloody diarrhea

• Liver toxicity: Yellowing of the skin/eyes (jaundice), dark urine

• Seizures: In patients with kidney issues or very high doses

• Severe skin reactions: Such as Stevens-Johnson syndrome

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🩺 Monitoring & Follow-Up

Monitoring is typically needed in long-term therapy or in special patient groups:

• Liver Function Tests (LFTs): Prolonged use may affect liver enzymes.

• Renal Function Tests (KFTs): Especially in elderly or renal-impaired patients.

• CBC (Complete Blood Count): For detecting allergic or hematologic responses.

• Watch for antibiotic-associated diarrhea or superinfections.

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⚠️ Warnings & Precautions

• Allergy: Avoid in patients allergic to penicillins or cephalosporins.

• Liver or Kidney Disease: Use with caution; dose adjustment may be needed.

• Pregnancy & Lactation: Generally safe but should be used under medical supervision.

• Alcohol: Not contraindicated, but alcohol may worsen side effects like nausea.

• Drug Interactions: May interfere with oral contraceptives or interact with methotrexate and allopurinol.

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📌 Summary

Amoxycillin 500mg + Clavulanic Acid 125mg Tablet is a powerful broad-spectrum antibiotic used to treat various bacterial infections, especially those caused by beta-lactamase-producing resistant organisms. Amoxycillin attacks bacterial cell walls, while clavulanic acid blocks resistance mechanisms, making the antibiotic more effective. It is generally well-tolerated, but monitoring is essential in patients with kidney or liver issues. Proper adherence to dosage and duration is key to treatment success and resistance prevention.

Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.