ATORSAVE GOLD 10 CAPSULE

🛡️💊 Aspirin 75mg + Atorvastatin 10mg + Clopidogrel 75mg Capsule: Triple Power for Heart Protection

This combination capsule containing Aspirin 75mg, Atorvastatin 10mg, and Clopidogrel 75mg delivers a comprehensive cardioprotective regimen for patients at risk of or recovering from cardiovascular and cerebrovascular events like heart attacks, stroke, angina, and post-stent placement. It combines an antiplatelet duo (Aspirin + Clopidogrel) with a cholesterol-lowering statin (Atorvastatin), offering synergistic protection by targeting blood clots, plaque buildup, and lipid imbalance—all major contributors to heart disease.

🔬 Mechanism of Action

Each component plays a crucial role in cardiovascular protection:

🔹 Aspirin (75mg) – Antiplatelet

• Irreversibly inhibits cyclooxygenase-1 (COX-1) enzyme

• Reduces thromboxane A2 formation, thereby preventing platelet aggregation

• Prevents blood clots that can cause heart attacks or strokes

🔹 Clopidogrel (75mg) – P2Y12 Platelet Inhibitor

• Irreversibly blocks ADP receptors (P2Y12) on platelets

• Works synergistically with aspirin to provide dual antiplatelet therapy (DAPT)

• Particularly useful after stent placement or in acute coronary syndromes

🔹 Atorvastatin (10mg) – Statin (HMG-CoA reductase inhibitor)

• Reduces LDL cholesterol, triglycerides, and mildly increases HDL cholesterol

• Stabilizes atherosclerotic plaques

• Has anti-inflammatory and endothelial-protective properties

Together, these three agents prevent plaque buildup, reduce the chance of clot formation, and improve long-term heart health.

📌 Indications and Uses

This fixed-dose combination is prescribed for:

• Secondary prevention of cardiovascular events in patients with:

  • Coronary artery disease (CAD)

  • Stroke or transient ischemic attacks (TIA)

  • Peripheral arterial disease (PAD)

• Post-myocardial infarction (MI)

• Post-angioplasty or stent placement

• Stable angina

• Diabetes with high cardiovascular risk

💊 Dosage and Administration

• One capsule once daily, preferably after dinner or as directed

• Should be taken with a full glass of water, not on an empty stomach

• Do not chew or crush the capsule

⚠️ Precautions and Warnings

• Bleeding risk: due to dual antiplatelet agents, monitor for signs of GI bleeding, bruising, or nosebleeds

• Liver function monitoring: Atorvastatin may elevate liver enzymes

• Kidney patients: use with caution

• Not recommended in:

  • Active bleeding disorders

  • Severe liver disease

  • Known allergy to any of the three drugs

Inform your doctor if you are on other anticoagulants, have a history of ulcers, or are undergoing surgery or dental work.

🤒 Side Effects

Common:

• Gastric irritation, nausea, indigestion

• Headache

• Muscle pain or weakness (statin-related)

• Easy bruising or bleeding

Serious:

• GI bleeding

• Myopathy or rhabdomyolysis (rare)

• Liver enzyme elevation

Seek urgent care if symptoms like dark urine, yellowing of eyes/skin, unusual bleeding, or severe muscle pain occur.

🔄 Drug Interactions

• Increased bleeding risk with NSAIDs, anticoagulants, SSRIs

• Grapefruit juice may increase statin levels—avoid consumption

• Monitor when combined with drugs affecting liver enzymes (CYP3A4)

🧊 Storage Instructions

• Store below 25°C, away from moisture and sunlight

• Keep in original blister pack

• Keep out of reach of children

📝 Conclusion

The Aspirin 75mg + Atorvastatin 10mg + Clopidogrel 75mg capsule offers a triple-action shield against cardiovascular events by targeting clot formation, high cholesterol, and vascular inflammation. It is a cornerstone therapy in cardiac care for high-risk patients, ensuring long-term protection when taken consistently and monitored properly.