CANDID TOTAL PLUS CREAM

🧴🦠🔥 Clobetasol 0.05% + Miconazole 2% + Neomycin 0.5% Cream: Triple-Action Relief for Inflammatory Skin Infections

This topical combination cream contains three potent agents—Clobetasol propionate 0.05%, Miconazole nitrate 2%, and Neomycin sulfate 0.5%—offering a powerful and comprehensive treatment for infected, inflamed, and fungal skin conditions. It is widely used in dermatology to treat mixed infections involving fungi, bacteria, and inflammation, especially in cases like eczema with superadded infection, dermatitis, ringworm, intertrigo, and infected fungal rashes.

🔬 Composition & Mechanism of Action

🔹 Clobetasol Propionate 0.05%

A super-potent corticosteroid, Clobetasol:

• Reduces inflammation, redness, itching, and swelling

• Suppresses the immune response to relieve autoimmune skin conditions

• Effective in eczema, psoriasis, and allergic dermatitis

🔹 Miconazole Nitrate 2%

An antifungal agent from the imidazole class, Miconazole:

• Inhibits ergosterol synthesis, damaging fungal cell membranes

• Treats dermatophytes, Candida, and yeast infections

• Helps in tinea infections, diaper rash, and cutaneous candidiasis

🔹 Neomycin Sulfate 0.5%

A broad-spectrum antibiotic, Neomycin:

• Inhibits bacterial protein synthesis

• Active against Gram-positive and Gram-negative bacteria

• Prevents or treats secondary bacterial infection

📌 Indications and Uses

This triple-combination cream is used for:

• Fungal skin infections with inflammation or secondary bacterial infection

• Infected eczema or dermatitis

• Candidiasis, tinea corporis, tinea cruris, and tinea pedis

• Intertrigo (rash in skin folds due to moisture and friction)

• Infected insect bites, contact dermatitis, or psoriatic plaques

• Mixed infections in skin folds, especially in diabetic or obese patients

💡 How to Use

• Apply a thin layer on the affected area 1–2 times daily, or as directed by a physician

• Do not cover with airtight dressing unless advised

• Avoid contact with eyes, nose, mouth, or broken skin

• Use for short durations (usually 5–7 days); extended use may increase side effects

⚠️ Precautions and Warnings

• Not for long-term use, especially on the face, groin, or armpits

• Avoid in:

  • Viral infections (e.g., herpes, chickenpox)

  • Tubercular or untreated fungal infections

  • Hypersensitivity to any ingredient

• Use cautiously in children, pregnancy, and breastfeeding

• Prolonged use may cause:

  • Skin thinning (atrophy)

  • Stretch marks (striae)

  • Topical steroid withdrawal reactions

🤒 Side Effects

Common:

• Skin irritation

• Burning or stinging sensation

• Dryness or redness

Prolonged use may lead to:

• Skin thinning

• Increased susceptibility to infections

• Delayed wound healing

• Contact allergy (especially from Neomycin)

Discontinue use and consult a doctor if irritation worsens or signs of allergic reaction appear.

🔄 Storage Instructions

• Store at below 25°C, away from heat and light

• Keep the cap tightly closed after use

• Keep out of reach of children

📝 Conclusion

This Clobetasol + Miconazole + Neomycin cream is a highly effective multi-purpose topical treatment for inflamed, infected fungal skin conditions. With its triple-action formula—anti-inflammatory, antifungal, and antibacterial—it quickly relieves symptoms and controls infection. However, due to the potency of clobetasol and neomycin, it must be used strictly under medical supervision to prevent resistance, irritation, or steroid-related skin damage.

Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.