CEFIX 200 TABLET

🦠💊 Cefixime 200mg Tablet: A Comprehensive Overview

Cefixime 200mg is a third-generation cephalosporin antibiotic used to treat a wide range of bacterial infections. It works by inhibiting the synthesis of bacterial cell walls, effectively stopping the growth and multiplication of the bacteria. Cefixime is available in tablet, capsule, and suspension forms, with 200mg being a common oral dosage prescribed for adolescents and adults.

🔍 Mechanism of Action

Cefixime is a beta-lactam antibiotic that targets and binds to penicillin-binding proteins (PBPs) located inside bacterial cell walls. By disrupting the final stage of bacterial cell wall synthesis, it causes the wall to rupture and the bacterium to die. It is bactericidal in nature and is effective against both gram-positive and gram-negative bacteria.

📋 Indications

Cefixime 200mg is prescribed for a variety of bacterial infections, including:

• Respiratory Tract Infections: Such as bronchitis, tonsillitis, pharyngitis.

• Urinary Tract Infections (UTIs): Including uncomplicated and complicated cases.

• Ear Infections: Otitis media.

• Sexually Transmitted Infections: Particularly uncomplicated gonorrhea.

• Sinusitis and other infections of the ENT (ear, nose, throat).

💡 Dosage & Administration

• Adults and adolescents (≥12 years): Typically one 200mg tablet once or twice daily depending on the infection’s severity.

• Can be taken with or without food, though food may improve absorption slightly.

• Duration: Generally ranges from 5 to 14 days, depending on the nature and severity of the infection.

⚠️ Always follow the physician’s prescription and do not discontinue the medication early, even if symptoms improve.

⚠️ Precautions & Warnings

• Allergies: Not suitable for individuals allergic to cephalosporins or penicillins.

• Kidney disease: Dose adjustment may be required.

• Pregnancy and breastfeeding: Use only if clearly needed; consult your doctor.

• Diabetic patients: The oral suspension may contain sugar—monitor blood sugar levels.

🤕 Side Effects

Common side effects include:

• Diarrhea

• Nausea

• Stomach pain

• Headache

Serious (rare) side effects may include:

• Severe allergic reactions (rash, itching, swelling)

• Clostridioides difficile-associated diarrhea

• Liver dysfunction (jaundice, abnormal liver tests)

Seek immediate medical help if you experience signs of an allergic reaction or persistent gastrointestinal distress.

🔄 Drug Interactions

• May interact with warfarin (increased bleeding risk).

• Live vaccines (e.g., typhoid) may be less effective while taking cefixime.

• Probenecid may increase cefixime levels by reducing its renal excretion.

🛡️ Storage & Handling

• Store tablets at room temperature away from moisture and heat.

• Keep out of reach of children.

• Do not use beyond the expiry date.

📝 Conclusion

Cefixime 200mg is a reliable, broad-spectrum antibiotic commonly used to treat a variety of infections. When taken as prescribed, it is generally safe and well-tolerated. However, it should not be used without medical supervision to avoid antibiotic resistance and potential side effects. Always complete the full course and consult a doctor for any concerns.