Description
💢💊🛠️ Drotaverine 80mg + Aceclofenac 100mg Tablet: Dual Relief for Pain & Muscle Spasms
The Drotaverine 80mg + Aceclofenac 100mg tablet is a fixed-dose combination medication used to provide rapid and effective relief from muscular pain, cramps, and inflammation. This powerful blend offers the antispasmodic benefits of Drotaverine and the anti-inflammatory, analgesic action of Aceclofenac, making it ideal for treating a wide range of painful musculoskeletal and abdominal conditions.
This dual-action therapy works synergistically to relieve pain, inflammation, and smooth muscle spasms, providing patients with quick symptomatic relief and improved comfort.
🔬 Mechanism of Action
🔹 Drotaverine (80mg) – Antispasmodic (smooth muscle relaxant)
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Inhibits phosphodiesterase-4 enzyme (PDE4), leading to increased cyclic AMP (cAMP) levels
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Relaxes smooth muscles in the gastrointestinal, biliary, and genitourinary tracts
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Provides relief from colicky and spastic pain, such as in renal colic, dysmenorrhea, or gallbladder pain
🔹 Aceclofenac (100mg) – NSAID (Non-Steroidal Anti-Inflammatory Drug)
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Inhibits cyclooxygenase (COX-1 and COX-2) enzymes
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Blocks the synthesis of prostaglandins, chemicals responsible for pain and inflammation
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Reduces swelling, stiffness, and pain in joints and muscles
Together, they address both the underlying inflammation and the associated muscle spasms, offering comprehensive pain relief.
📌 Indications and Uses
This combination is commonly used for:
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Menstrual cramps (dysmenorrhea)
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Renal colic (kidney stones)
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Biliary colic (gallbladder pain)
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Musculoskeletal pain
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Post-operative pain with muscle spasm
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Pelvic inflammatory pain
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Irritable bowel syndrome (IBS) with cramping
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Dental pain
Its dual mechanism makes it effective in both acute and chronic pain conditions where inflammation and spasm coexist.
💊 Dosage and Administration
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Usual adult dose: 1 tablet twice daily, after meals
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Dosage may vary based on clinical condition and medical advice
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Take with food to minimize gastric irritation
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Not recommended for children under 12 years unless prescribed by a doctor
⚠️ Precautions and Warnings
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Use cautiously in:
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Patients with gastric ulcers, GERD, or bleeding disorders
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Renal or hepatic impairment
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Elderly patients
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Avoid in:
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Pregnancy, especially third trimester
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Lactation, unless clearly needed
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Known allergy to NSAIDs or Drotaverine
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🤒 Side Effects
Common side effects:
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Gastric discomfort, nausea
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Headache or dizziness
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Dry mouth
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Mild abdominal bloating
Serious (rare):
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Gastric bleeding or ulcers (Aceclofenac-related)
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Allergic reactions (rash, swelling, difficulty breathing)
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Liver enzyme elevation
Seek immediate medical attention if you notice blood in stools, severe stomach pain, or allergic symptoms.
🔄 Drug Interactions
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Avoid with:
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Other NSAIDs (e.g., Ibuprofen, Diclofenac) – increased risk of GI side effects
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Anticoagulants (e.g., warfarin) – increased bleeding risk
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Antihypertensives – NSAIDs may reduce their effectiveness
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🧊 Storage Instructions
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Store at room temperature (15–25°C)
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Keep away from moisture, heat, and direct sunlight
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Keep out of reach of children
📝 Conclusion
The Drotaverine 80mg + Aceclofenac 100mg tablet is a potent and fast-acting combination designed to relieve spasmodic pain accompanied by inflammation. Whether it’s renal colic, menstrual cramps, or joint pain, this dual therapy provides targeted relief, making it a valuable choice for physicians and patients managing complex pain conditions.
Note: This information is intended for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for personalized guidance.
